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Literature DB >> 5273453

Protein chain initiation in rabbit reticulocytes.

Abstract

About 15% of the nascent alpha-chains isolated from in vivo labeled rabbit reticulocytes have methionine as their amino terminal amino acid. The methionine is predominantly on the shortest nascent chains, suggesting that methionine initiates the synthesis of rabbit hemoglobin and is rapidly removed during further synthesis.

Entities: Chemical Species

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Year: 1970 PMID： 5273453 PMCID： PMC335817 DOI： 10.1073/pnas.66.4.1282

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

17 in total

1. N-FORMYL-METHIONYL-S-RNA.

Authors: K MARCKER; F SANGER
Journal: J Mol Biol Date: 1964-06 Impact factor: 5.469

2. PHAGE f2 RNA-DIRECTED BINDING OF FORMYLMETHIONYL-TRNA TO RIBOSOMES AND THE ROLE OF 30S RIBOSOMAL SUBUNITS IN INITIATION OF PROTEIN SYNTHESIS.

Authors: M Nomura; C V Lowry
Journal: Proc Natl Acad Sci U S A Date: 1967-09 Impact factor: 11.205

3. Deacylated transfer ribonucleic acid as a factor for peptide chain initiation in rabbit reticulocyte systems.

Authors: R D Mosteller; W J Culp; B Hardesty
Journal: J Biol Chem Date: 1968-12-25 Impact factor: 5.157

4. Selective utilization of nonformylatable species of methionyl-tRNA's from Escherichia coli and yeast in a reticulocyte cell-free system.

Authors: K Takeishi; T Sekiya; T Ukita
Journal: Biochim Biophys Acta Date: 1970-02-18

5. Initiation of hemoglobin synthesis with rabbit and E. coli tRNA in a reticulocyte cell-free system.

Authors: F Gonano; C Baglioni
Journal: Eur J Biochem Date: 1969-11

6. Purification of histidine-specific transfer RNA from yeast.

Authors: K Takeishi; S Nishimura; T Ukita
Journal: Biochim Biophys Acta Date: 1967

7. The presence of N-formyl-methionyl-tRNA in HeLa cell mitochondria.

Authors: J B Galper; J E Darnell
Journal: Biochem Biophys Res Commun Date: 1969-01-27 Impact factor: 3.575

8. Involvement of N-formylmethionine in initiation of protein synthesis in cell-free extracts of Euglena gracilis.

Authors: J H Schwartz; R Meyer; J M Eisenstadt; G Brawerman
Journal: J Mol Biol Date: 1967-05-14 Impact factor: 5.469

9. N-formylmethionyl-sRNA as the initiator of protein synthesis.

Authors: J M Adams; M R Capecchi
Journal: Proc Natl Acad Sci U S A Date: 1966-01 Impact factor: 11.205

10. N-formylmethionyl transfer RNA in mitochondria from yeast and rat liver.

Authors: A E Smith; K A Marcker
Journal: J Mol Biol Date: 1968-12-14 Impact factor: 5.469

19 in total

1. Ability of formyl-methionyl-tRNA to initiate globin synthesis in the presence of double-stranded RNA or in the absence of hemin.

Authors: F Cahn; M Lubin
Journal: Mol Biol Rep Date: 1975-03 Impact factor: 2.316

2. Specificity of lens initiator tRNA for N-terminal recognition.

Authors: G J Strous; H Bloemendal
Journal: Mol Biol Rep Date: 1973-08 Impact factor: 2.316

3. Hemoglobin Long Island is caused by a single mutation (adenine to cytosine) resulting in a failure to cleave amino-terminal methionine.

Authors: J T Prchal; D P Cashman; Y W Kan
Journal: Proc Natl Acad Sci U S A Date: 1986-01 Impact factor: 11.205

4. Translation of bacteriophage Q RNA by cytoplasmic extracts of mammalian cells.

Authors: T G Morrison; H F Lodish
Journal: Proc Natl Acad Sci U S A Date: 1973-02 Impact factor: 11.205

5. Amino-terminal processing of proteins: hemoglobin South Florida, a variant with retention of initiator methionine and N alpha-acetylation.

Authors: J P Boissel; T J Kasper; S C Shah; J I Malone; H F Bunn
Journal: Proc Natl Acad Sci U S A Date: 1985-12 Impact factor: 11.205