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Literature DB >> 5271746

Demonstration of delayed hypersensitivity to soluble antigens of chemically induced tumors by inhibition of macrophage migration.

B R Bloom, B Bennett, H F Oettgen, E P McLean, L J Old.

Abstract

Sensitization to soluble antigens of chemically induced tumors is demonstrable in syngeneic strain 13 (inbred) guinea pigs by specific inhibition of macrophage migration. According to their capacity to (a) inhibit the migration of peritoneal cells from sensitized strain 13 donors or (b) release migration-inhibitory factor from their lymph node cells, the soluble antigens of three different chemically induced tumors did not cross react. This is in keeping with the absence of cross-reactivity among the same three tumors in previous tests of transplantation resistance or delayed hypersensitivity in vivo. Thus, inhibition of macrophage migration may provide a feasible assay in vitro for use in defining these soluble antigens further by physicochemical methods.

Entities: Disease Species

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Year: 1969 PMID： 5271746 PMCID： PMC223265 DOI： 10.1073/pnas.64.4.1176

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

11 in total

1. DELAYED HYPERSENSITIVITY IN VITRO. I. THE SPECIFICITY OF INHIBITION OF CELL MIGRATION BY ANTIGENS.

Authors: J R DAVID; S AL-ASKARI; H S LAWRENCE; L THOMAS
Journal: J Immunol Date: 1964-08 Impact factor: 5.422

2. In vitro cell migration as a model for delayed hypersensitivity.

Authors: M GEORGE; J H VAUGHAN
Journal: Proc Soc Exp Biol Med Date: 1962-11

3. Tumor-specific antigens detected by inhibition of macrophage migration.

Authors: B S Kronman; H T Wepsic; W H Churchill; B Zbar; T Borsos; H J Rapp
Journal: Science Date: 1969-07-18 Impact factor: 47.728

4. Migration inhibitory factor associated with delayed-type hypersensitivity.

Authors: B R Bloom; B Bennett
Journal: Fed Proc Date: 1968 Jan-Feb

5. Delayed hypersensitivity and transplantation immunity elicited by soluble antigens of chemically induced tumours in inbred guinea-pigs.

Authors: H F Oettgen; L J Old; E P McLean; E A Carswell
Journal: Nature Date: 1968-10-19 Impact factor: 49.962

6. In vitro detection of guinea pig alloantigens by the macrophage-inhibition technique.

Authors: R A Malmgren; E C Holmes; D L Morton; C L Yee; J Marrone; M W Myers
Journal: Transplantation Date: 1969-10 Impact factor: 4.939

7. Reactions in vivo and in vitro produced by a soluble substance associated with delayed-type hypersensitivity.

Authors: B Bennett; B R Bloom
Journal: Proc Natl Acad Sci U S A Date: 1968-03 Impact factor: 11.205

8. Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction.

Authors: J R David
Journal: Proc Natl Acad Sci U S A Date: 1966-07 Impact factor: 11.205

9. Mechanism of a reaction in vitro associated with delayed-type hypersensitivity.

Authors: B R Bloom; B Bennett
Journal: Science Date: 1966-07-01 Impact factor: 47.728

10. Demonstration of delayed (tuberculin) type hypersensitivity in vitro. II. Specific reaction of hypersensitive cells with antigen.

Authors: J SVEJCAR; J JOHANOVSKY
Journal: Z Immun exp ther Date: 1961-12

11 in total

Review 1. Cytokine reporter mice in immunological research: perspectives and lessons learned.

Authors: Andrew L Croxford; Thorsten Buch
Journal: Immunology Date: 2010-11-11 Impact factor: 7.397

Review 2. The biological activities of soluble lymphocyte products.

Authors: E Pick; J L Turk
Journal: Clin Exp Immunol Date: 1972-01 Impact factor: 4.330

3. Migration inhibitory factor and the cellular basis of delayed-type hypersensitivity reactions.

Authors: B R Bloom; L Jimenez
Journal: Am J Pathol Date: 1970-09 Impact factor: 4.307

4. Characterization of Neospora caninum macrophage migration inhibitory factor.

Authors: Guanggang Qu; Raymond Fetterer; Mark Jenkins; Lin Leng; Zhiqiang Shen; Charles Murphy; Wenyu Han; Richard Bucala; Wenbin Tuo
Journal: Exp Parasitol Date: 2013-07-11 Impact factor: 2.011

5. Migration inhibition of mouse macrophages by Brucella antigens.

Authors: P L Sandok; R D Hinsdill; R M Albrecht
Journal: Infect Immun Date: 1971-10 Impact factor: 3.441

6. Delayed Hypersensitivity Induced in Guinea Pigs by 7, 12-Dimethylbenz(a) anthracene.

Authors: D R Burger; L E Irish; R M Vetto; D J Hinrichs
Journal: Infect Immun Date: 1971-03 Impact factor: 3.441

7. Brain miffed by macrophage migration inhibitory factor.

Authors: Nic E Savaskan; Günter Fingerle-Rowson; Michael Buchfelder; Ilker Y Eyüpoglu
Journal: Int J Cell Biol Date: 2012-09-03

8. Transcriptome analysis of epigenetically modulated genome indicates signature genes in manifestation of type 1 diabetes and its prevention in NOD mice.

Authors: Sundararajan Jayaraman; Akshay Patel; Arathi Jayaraman; Vasu Patel; Mark Holterman; Bellur Prabhakar
Journal: PLoS One Date: 2013-01-30 Impact factor: 3.240

9. Cellular immune responses to methylcholanthrene-induced fibrosarcoma in BALB/c mice.

Authors: R M Bhatnagar; J B Zabriskie; A R Rausen
Journal: J Exp Med Date: 1975-10-01 Impact factor: 14.307

10. Production of macrophage migration inhibition factor by continuous cell lines.

Authors: D G Tubergen; J D Feldman; E M Pollock; R A Lerner
Journal: J Exp Med Date: 1972-02-01 Impact factor: 14.307