Literature DB >> 16557998

Delayed Hypersensitivity Induced in Guinea Pigs by 7, 12-Dimethylbenz(a) anthracene.

D R Burger1, L E Irish, R M Vetto, D J Hinrichs.   

Abstract

A delayed hypersensitivity to 7, 12-dimethylbenz(a)anthracene was elicited in guinea pigs after contact sensitization. This sensitivity was characterized by its time of appearance, histology, specificity, and transfer characteristics. The reaction had its maximal dermal reactivity 24 hr after challenge, was characterized by a mononuclear cell infiltration, demonstrated immunological specificity, and could be transferred with leukocytes to normal animals.

Entities:  

Year:  1971        PMID： 16557998      PMCID： PMC416176          DOI： 10.1128/iai.3.3.478-480.1971

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  5 in total

1.  Contact reactivity to carcinogenic polycyclic hydrocarbons.

Authors:  L J OLD; B BENACERRAF; E CARSWELL
Journal:  Nature       Date:  1963-06-22       Impact factor: 49.962

2.  Passive transfer of delayed hypersensitivity to 2,4-dinitrochlorobenzene in guinea pigs with leucocytic extracts.

Authors:  W S JETER; M M TREMAINE; P M SEEBOHM
Journal:  Proc Soc Exp Biol Med       Date:  1954-06

3.  [On the carcinoresistance of the guinea pig. Experimental tumors in the guinea pig. II].

Authors:  M MOSINGER
Journal:  Bull Assoc Fr Etud Cancer       Date:  1961 Oct-Dec

4.  Delayed hypersensitivity and transplantation immunity elicited by soluble antigens of chemically induced tumours in inbred guinea-pigs.

Authors:  H F Oettgen; L J Old; E P McLean; E A Carswell
Journal:  Nature       Date:  1968-10-19       Impact factor: 49.962

5.  Demonstration of delayed hypersensitivity to soluble antigens of chemically induced tumors by inhibition of macrophage migration.

Authors:  B R Bloom; B Bennett; H F Oettgen; E P McLean; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1969-12       Impact factor: 11.205
  5 in total

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