Literature DB >> 5264149

Identification of a bacterial growth inhibitors from HeLa cells: a ketoaldehyde.

B G Sparkes, C P Kenny.   

Abstract

The growth-inhibiting factor found earlier in human cell cultures appeared to be a ketoaldehyde. An infrared spectral study of 2,4-dinitrophenylhydrazine derivatives suggested that the ketoaldehyde was 4-hydroxy-2-ketobutyraldehyde. The compound, when synthesized, gave the same DNPH derivatives as the natural substance.

Entities:  

Mesh：

Substances：

Year:  1969        PMID： 5264149      PMCID： PMC223322          DOI： 10.1073/pnas.64.3.920

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  20 in total

1.  Evaluation of potential antirheumatic drugs in vitro using lymphocytes and epithelial cells. The selective action of indoxole, methyl glyoxal and chloroquine.

Authors:  M W Whitehouse
Journal:  J Pharm Pharmacol       Date:  1967-09       Impact factor: 3.765

2.  [On the inactivating action in vitro of some ketoaldehyde derivatives on encephalomyocarditis (EMC) virus and aphthous (FMD) virus].

Authors:  G Tarro; A Frasca
Journal:  Boll Soc Ital Biol Sper       Date:  1964-10-31

Review 3.  Keto-aldehydes and cell division.

Authors:  A Szent-Györgyi; L G Együd; J A McLaughlin
Journal:  Science       Date:  1967-02-03       Impact factor: 47.728

4.  The effect of methylglyoxal on phage infection of Escherichia coli.

Authors:  M B Baylor; L G Együd
Journal:  Virology       Date:  1967-02       Impact factor: 3.616

5.  Cell division, SH, ketoaldehydes, and cancer.

Authors:  L G Együd; A Szent-Györgyi
Journal:  Proc Natl Acad Sci U S A       Date:  1966-02       Impact factor: 11.205

6.  Ketone aldehydes in animal tissues.

Authors:  G Fodor; J P Sachetto; A Szent-Györgyi; L G Együd
Journal:  Proc Natl Acad Sci U S A       Date:  1967-06       Impact factor: 11.205

7.  Studies on autobiotics: chemical nature of retine.

Authors:  L G Együd
Journal:  Proc Natl Acad Sci U S A       Date:  1965-07       Impact factor: 11.205

8.  [Comparative study of some ketoaldehyde derivatives in relation to their inactivating action in vitro on A-PR8 influenza virus].

Authors:  G Lorenzutti; U Sapio; E Esposito
Journal:  Boll Soc Ital Biol Sper       Date:  1964-10-31

9.  [On the inactivating action in vitro of some ketoaldehyde derivatives on arboviruses].

Authors:  P Altucci; G Tarro
Journal:  Boll Soc Ital Biol Sper       Date:  1964-10-31

10.  Antiviral compounds. 8. Aminoacethydrazones of aromatic alpha-ketoaldehydes.

Authors:  E Massarani; D Nardi; L Degen; M J Magistretti
Journal:  J Med Chem       Date:  1966-07       Impact factor: 7.446
View more
  1 in total

1.  Purification of 2-oxoaldehyde dehydrogenase and its dependence on unusual amines.

Authors:  J Dunkerton; S P James
Journal:  Biochem J       Date:  1975-09       Impact factor: 3.857
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.