Literature DB >> 5259770

Amino acid sequence restriction in rabbit antibody light chains.

L Hood, H Lackland, K Eichman, T J Kindt, D G Braun, R M Krause.   

Abstract

Light chains were obtained from IgG rabbit antibodies to the group-specific carbohydrates of groups A and C streptococci. An analysis of the amino acid alternatives which exist at the first three positions of the N-terminus in both light-chain preparations shows a marked restriction in amino acid sequence heterogeneity when compared with preimmune light chains. Both of these related, but immunologically distinct, antigenic determinants select the same uncommon subpopulation of rabbit light chains.

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Year:  1969        PMID： 5259770      PMCID： PMC223536          DOI： 10.1073/pnas.63.3.890

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  The amino-terminal amino acid sequences of rabbit immunoglobulin light chains.

Authors:  R F Doolittle
Journal:  Proc Natl Acad Sci U S A       Date:  1966-05       Impact factor: 11.205

Review 3.  Immunoglobulin structure: variability and homology.

Authors:  F W Putnam
Journal:  Science       Date:  1969-02-14       Impact factor: 47.728

4.  Chemical and immunochemical evidence for different classes of rabbit light polypeptide chains.

Authors:  E Appella; R G Mage; S Dubiski; R A Reisfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1968-07       Impact factor: 11.205

5.  Hydrolysis of phenylthiohydantoins of amino acids.

Authors:  H O Van Orden; F H Carpenter
Journal:  Biochem Biophys Res Commun       Date:  1964       Impact factor: 3.575

6.  Structure of antibody molecules.

Authors:  S Cohen; C Milstein
Journal:  Nature       Date:  1967-04-29       Impact factor: 49.962

7.  The individual antigenic specificity of antibodies to streptococcal carbohydrates.

Authors:  D G Braun; R M Krause
Journal:  J Exp Med       Date:  1968-11-01       Impact factor: 14.307

8.  Electrophoretic heterogeneity of polypeptide chains of specific antibodies.

Authors:  R A Reisfeld; P A Small
Journal:  Science       Date:  1966-05-27       Impact factor: 47.728

9.  Quantitative variations in L chain types in guinea pig antihapten antibodies.

Authors:  V Nussenzweig; B Benacerraf
Journal:  J Exp Med       Date:  1966-11-01       Impact factor: 14.307

10.  Rabbit antibodies to streptococcal carbohydrates. Influence of primary and secondary immunization and of possible genetic factors on the antibody response.

Authors:  D G Braun; K Eichmann; R M Krause
Journal:  J Exp Med       Date:  1969-04-01       Impact factor: 14.307
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  9 in total

1.  Electrophoretically homogeneous anti-DNP antibodies with restricted isoelectric points elicited in mice by immunization with the antigen papain-S-DNPL.

Authors:  G N Trump; S J Singer
Journal:  Proc Natl Acad Sci U S A       Date:  1970-06       Impact factor: 11.205

Review 2.  [Immune response with monoclonal differentiation].

Authors:  D G Braun
Journal:  Klin Wochenschr       Date:  1971-12-01

3.  A comparison of the N-terminal amino acid sequences of early and late pools of anti-DNP and anti-DNP-p-aminobenzoylglutamate antibody light chains.

Authors:  D M Hagins; V H Bray; J Henke; R E Lovins
Journal:  Immunology       Date:  1978-05       Impact factor: 7.397

4.  Homogeneous antibody elicited with dinitrophenyl-gramicidin-S (rabbit-isoelectric focusing).

Authors:  P C Montgomery; J H Rockey; A R Williamson
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

5.  Immune response of rats to group A streptococcal vaccine.

Authors:  G A Leslie; H F Carwile
Journal:  Infect Immun       Date:  1973-05       Impact factor: 3.441

6.  The emergence of antibodies with either identical or unrelated individual antigenic specificity during repeated immunizations with streptococcal vaccines.

Authors:  K Eichmann; D G Braun; T Feizi; R M Krause
Journal:  J Exp Med       Date:  1970-06-01       Impact factor: 14.307

7.  Allotype exclusion in uniform rabbit antibody to streptococcal carbohydrate.

Authors:  T J Kindt; C W Todd; K Eichmann; R M Krause
Journal:  J Exp Med       Date:  1970-02       Impact factor: 14.307

8.  Idiotype expression and the inheritance of mouse antibody clones.

Authors:  K Eichmann
Journal:  J Exp Med       Date:  1973-03-01       Impact factor: 14.307

9.  Induction of rabbit antibody with molecular uniformity after immunization with group C streptococci.

Authors:  K Eichmann; H Lackland; L Hood; R M Krause
Journal:  J Exp Med       Date:  1970-01-01       Impact factor: 14.307
  9 in total

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