Literature DB >> 4536669

Homogeneous antibody elicited with dinitrophenyl-gramicidin-S (rabbit-isoelectric focusing).

P C Montgomery, J H Rockey, A R Williamson.   

Abstract

Rabbit antibody to dinitrophenyl hapten has been elicited by hyperimmunization with a bifunctional cyclic decapeptide antigen, di-dinitrophenyl-gramicidin-S. Examination of the induced antibody by isoelectric focusing, and Sipsian analysis of the haptenbinding data, demonstrated that di-dinitrophenyl-gramicidin-S was capable of stimulating and maintaining the production of a biosynthetically homogeneous antibody in the adult animal.

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Year:  1972        PMID: 4536669      PMCID: PMC427581          DOI: 10.1073/pnas.69.1.228

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  20 in total

1.  Preparation of iodine-131 labelled human growth hormone of high specific activity.

Authors:  W M HUNTER; F C GREENWOOD
Journal:  Nature       Date:  1962-05-05       Impact factor: 49.962

2.  Ability of CBA mice to produce anti-idiotypic sera to 5563 myeloma protein.

Authors:  G M Iverson
Journal:  Nature       Date:  1970-07-18       Impact factor: 49.962

3.  Mouse myeloma proteins with antihapten antibody acitivity. The protein produced by plasma cell tumor MOPC-315.

Authors:  H N Eisen; E S Simms; M Potter
Journal:  Biochemistry       Date:  1968-11       Impact factor: 3.162

4.  A Waldenström macroglobulin which binds nitrophenyl ligands.

Authors:  R F Ashman; H Metzger
Journal:  J Biol Chem       Date:  1969-06-25       Impact factor: 5.157

5.  Determination of antibody-hapten equilibrium constants by an ammonium sulfate precipitation technique.

Authors:  Y Stupp; T Yoshida; W E Paul
Journal:  J Immunol       Date:  1969-09       Impact factor: 5.422

6.  Electrophoretically homogeneous anti-DNP antibodies with restricted isoelectric points elicited in mice by immunization with the antigen papain-S-DNPL.

Authors:  G N Trump; S J Singer
Journal:  Proc Natl Acad Sci U S A       Date:  1970-06       Impact factor: 11.205

7.  Molecular restriction of anti-hapten antibody elicited in neonatal rabbits.

Authors:  P C Montgomery; A R Williamson
Journal:  Nature       Date:  1970-12-26       Impact factor: 49.962

8.  The homogeneous-gamma-G-immunoglobulin produced by mouse plasmacytoma 5563 and its subsequent heterogeneity in serum.

Authors:  Z L Awdeh; B A Askonas; A R Williamson
Journal:  Biochem J       Date:  1967-02       Impact factor: 3.857

9.  Selection of a single antibody-forming cell clone and its propagation in syngeneic mice.

Authors:  B A Askonas; A R Williamson; B E Wright
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205

10.  One cell-one immunoglobulin. Origin of limited heterogeneity of myeloma proteins.

Authors:  Z L Awdeh; A R Williamson; B A Askonas
Journal:  Biochem J       Date:  1970-01       Impact factor: 3.857

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  6 in total

Review 1.  Extent and control of antibody diversity.

Authors:  A R Williamson
Journal:  Biochem J       Date:  1972-11       Impact factor: 3.857

2.  Characterization of an antibody directed against a surface component of normal and pleomorphic cells of Streptococcus sanguis.

Authors:  R J Eisenberg; P C Montgomery
Journal:  Infect Immun       Date:  1975-09       Impact factor: 3.441

3.  The mechanism of antigenic stimulation of primary and secondary clonal precursor cells.

Authors:  N R Klinman
Journal:  J Exp Med       Date:  1972-08-01       Impact factor: 14.307

4.  Alteration of clonal profile. I. Effect of sublethal irradiation on the responses to phosphorylcholine in BALB/c mice.

Authors:  D R Kaplan; J Quintáns
Journal:  J Exp Med       Date:  1978-10-01       Impact factor: 14.307

5.  Hapten-specific hemolytic plaque assays usually fail to detect most of the diversity in the anti-hapten response.

Authors:  B Merchant; J K Inman
Journal:  J Exp Med       Date:  1977-02-01       Impact factor: 14.307

6.  Experimental studies on the bridging hypothesis of anaphylaxis: haptenic determinants required to elicit immediate-type reactions in calf skin by separate or concurrent sensitization with reagins of different specificity.

Authors:  H Mossmann; M Meyer-Delius; U Vortisch; B Kickhöfen; D K Hammer
Journal:  J Exp Med       Date:  1974-12-01       Impact factor: 14.307

  6 in total

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