Literature DB >> 5253654

On the conformational instability of human serum low-density lipoprotein: effect of temperature.

A Scanu, H Pollard, R Hirz, K Kothary.   

Abstract

When examined by circular dichroism and ultraviolet spectroscopy, human serum low-density lipoprotein (LDL) and its delipidated product, apo LDL, exhibited reversible thermal changes. The more marked temperature sensitivity of apo LDL as compared to LDL was taken to support a constraining role by lipids on the observed structural instability of the apoprotein.

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Year:  1969        PMID： 5253654      PMCID： PMC285970          DOI： 10.1073/pnas.62.1.171

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  14 in total

1.  Solubilization and properties of the apoproteins of the very low- and low-density lipoproteins of human serum.

Authors:  J L Granda; A Scanu
Journal:  Biochemistry       Date:  1966-10       Impact factor: 3.162

2.  Human serum beta-lipoprotein: preparation and properties of a delipidated, soluble derivative.

Authors:  A M Gotto; R I Levy; D S Fredrickson
Journal:  Biochem Biophys Res Commun       Date:  1968-04-19       Impact factor: 3.575

3.  Human serum low-density lipoprotein protein: its conformation studied by circular dichroism.

Authors:  A Scanu; R Hirz
Journal:  Nature       Date:  1968-04-13       Impact factor: 49.962

4.  On the structure of human serum high-density lipoprotein: studies by the technique of circular dichroism.

Authors:  A Scanu; R Hirz
Journal:  Proc Natl Acad Sci U S A       Date:  1968-03       Impact factor: 11.205

5.  The optical rotatory properties of the beta-configuration in polypeptides and proteins.

Authors:  P K Sarkar; P Doty
Journal:  Proc Natl Acad Sci U S A       Date:  1966-04       Impact factor: 11.205

6.  Optical rotatory dispersion of nonhelical proteins.

Authors:  B Jirgensons
Journal:  J Biol Chem       Date:  1966-01-10       Impact factor: 5.157

7.  The optical rotatory dispersion of two beta structures.

Authors:  G D Fasman; J Potter
Journal:  Biochem Biophys Res Commun       Date:  1967-04-20       Impact factor: 3.575

8.  The protein moiety of human serum beta-lipoproteins.

Authors:  B Shore; V Shore
Journal:  Biochem Biophys Res Commun       Date:  1967-09-27       Impact factor: 3.575

9.  The circular dichroism of the beta structure of poly-L-lysine.

Authors:  R Townend; T F Kumosinski; S N Timasheff; G D Fasman; B Davidson
Journal:  Biochem Biophys Res Commun       Date:  1966-04-19       Impact factor: 3.575

10.  Properties of human serum low density lipoproteins after modification by succinic anhydride.

Authors:  A Scanu; H Pollard; W Reader
Journal:  J Lipid Res       Date:  1968-05       Impact factor: 5.922
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  16 in total

1.  Solubilization of apolipoprotein B and its specific binding by the cellular receptor for low density lipoprotein.

Authors:  R Shireman; L L Kilgore; W R Fisher
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

2.  Ribonucleic acid synthesis and transport in animal cells at 27 degrees C.

Authors:  M Horisberger; H Amos
Journal:  Biochem J       Date:  1970-04       Impact factor: 3.857

3.  On the geometrical arrangement of the protein subunits of human serum low-density lipoprotein: evidence for a dodecahedral model.

Authors:  H Pollard; A M Scanu; E W Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  1969-09       Impact factor: 11.205

4.  Spinach Thylakoid Polyphenol Oxidase : ISOLATION, ACTIVATION, AND PROPERTIES OF THE NATIVE CHLOROPLAST ENZYME.

Authors:  J H Golbeck; K V Cammarata
Journal:  Plant Physiol       Date:  1981-05       Impact factor: 8.340

5.  Quantification of an apoprotein of pulmonary surfactant in normal and alloxan-induced diabetic rats by electroimmunoassay.

Authors:  K Sugahara; H Maeda; K I Yamashiro; H Kohda; T Okazaki; T Morioka
Journal:  Lung       Date:  1983       Impact factor: 2.584

6.  The structure of plasma low density lipoproteins: experimental facts and interpretations--a minireview.

Authors:  T Kirchhausen; G Fless; A M Scanu
Journal:  Lipids       Date:  1980-06       Impact factor: 1.880

7.  Circular dichroic, infrared and other studies on the protein component of pig brain thromboplastin.

Authors:  R M Howell; H Rezvan
Journal:  Biochem J       Date:  1980-08-01       Impact factor: 3.857

Review 8.  [Lipid-protein-interactions of human apolipoproteins-structural aspects and models of lipoproteins (author's transl)].

Authors:  G Middelhoff; J Augustin; G Klose; H Greten
Journal:  Klin Wochenschr       Date:  1977-02-15

9.  Isolation and chemical composition of surface-active material from human lung lavage.

Authors:  T Sadana; K Dhall; S N Sanyal; A Wali; R Minocha; S Majumdar
Journal:  Lipids       Date:  1988-06       Impact factor: 1.880

10.  A comparaive study of the effects of chemical modification on the immunochemical and optical properties of human plasma low-density lipoprotein(s) and apoproteins.

Authors:  A M Gotto; R I Levy; S E Lux; M E Birnbaumer; D S Fredrickson
Journal:  Biochem J       Date:  1973-06       Impact factor: 3.857
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