Literature DB >> 521009

Glucose, insulin and somatostatin infusion for the determination of insulin resistance in liver cirrhosis.

A V Greco, A G Rebuzzi, L Altomonte, R Manna, A Bertoli, G Ghirlanda.   

Abstract

Twelve patients with liver cirrhosis and ten normal subjects were studied. Using a constant intravneous infusion of glucose, insulin and somatostatin over 2 1/2 hours we determined the stteady state plasma glucose level (SSPG) in order to measure insulin resistance. The results demonstrated that the cirrhotic patients were insulin resistant compared to normals and that plasma glucagon does not account for the insulin resistance in these patients.

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Year:  1979        PMID： 521009     DOI： 10.1055/s-0028-1092777

Source DB:  PubMed          Journal:  Horm Metab Res        ISSN： 0018-5043            Impact factor:   2.936


  7 in total

1.  Insulin resistance in porphyria cutanea tarda.

Authors:  F Calcinaro; G Basta; P Lisi; C Cruciani; M Pietropaolo; F Santeusanio; A Falorni; R Calafiore
Journal:  J Endocrinol Invest       Date:  1989-06       Impact factor: 4.256

2.  Mechanisms of hyperinsulinaemia in Child's disease grade B liver cirrhosis investigated in free living conditions.

Authors:  A V Greco; G Mingrone; A Mari; E Capristo; M Manco; G Gasbarrini
Journal:  Gut       Date:  2002-12       Impact factor: 23.059

3.  In vivo insulin action in hepatocellular and cholestatic liver cirrhosis.

Authors:  N Barzilai; P Cohen; E Karnieli; R Enat; O Epstein; J Owen; N McIntyre
Journal:  J Endocrinol Invest       Date:  1991-10       Impact factor: 4.256

4.  Insulin resistance is the main determinant of impaired glucose tolerance in patients with liver cirrhosis.

Authors:  G Marchesini; G P Bianchi; G Forlani; A G Rusticali; D Patrono; M Capelli; M Zoli; P Vannini; E Pisi
Journal:  Dig Dis Sci       Date:  1987-10       Impact factor: 3.199

5.  Mechanism of insulin resistance in human liver cirrhosis. Evidence of a combined receptor and postreceptor defect.

Authors:  P Cavallo-Perin; M Cassader; C Bozzo; A Bruno; P Nuccio; A M Dall'Omo; M Marucci; G Pagano
Journal:  J Clin Invest       Date:  1985-05       Impact factor: 14.808

6.  Decreased insulin binding to red blood cells in liver cirrhosis.

Authors:  A V Greco; A Bentoli; S Caputo; L Altomonte; R Manna; G Ghirlanda
Journal:  Acta Diabetol Lat       Date:  1983 Jul-Sep

7.  Possible roles of insulin, glucagon, growth hormone and free fatty acids in the pathogenesis of insulin resistance of subjects with chronic liver diseases.

Authors:  E Bonora; S Orioli; C Coscelli; G Buzzelli; P Gentilini; U Butturini
Journal:  Acta Diabetol Lat       Date:  1984 Jul-Sep
  7 in total

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