Literature DB >> 518571

N-formyl-L-methionine deformylase activity in human leucocytes and platelets.

S K Ackerman, S D Douglas.   

Abstract

Extracts of human neutrophils, lymphocytes and platelets enzymically deformylate N-formyl-L-methionine. Enzyme activity is stimulated by Co2+, inhibited by bivalent-cation chelators and unaffected by inhibitors of serine, thiol and carboxyl proteinases. Leucocyte or platelet N-formylmethionine deformylase may be important in modulation of neutrophil responses to chemoattractant formylmethionyl peptides or similar compounds.

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Year:  1979        PMID： 518571      PMCID： PMC1161425          DOI： 10.1042/bj1820885

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  8 in total

1.  The isolation and partial characterization of neutrophil chemotactic factors from Escherichia coli.

Authors:  E Schiffmann; H V Showell; B A Corcoran; P A Ward; E Smith; E L Becker
Journal:  J Immunol       Date:  1975-06       Impact factor: 5.422

2.  Specificity of amino acid acylases.

Authors:  S M BIRNBAUM; L LEVINTOW; R B KINGSLEY; J P GREENSTEIN
Journal:  J Biol Chem       Date:  1952-01       Impact factor: 5.157

3.  N-Formyl-methionine deformylase of animal tissues.

Authors:  S Grisolia; A Reglero; J Rivas
Journal:  Biochem Biophys Res Commun       Date:  1977-07-11       Impact factor: 3.575

4.  Amidohydrolase activity of Escherichia coli extracts with formylated amino acids and dipeptides as substrates.

Authors:  K T Fry; M R Lamborg
Journal:  J Mol Biol       Date:  1967-09-28       Impact factor: 5.469

5.  On the release of the formyl group from nascent protein.

Authors:  J M Adams
Journal:  J Mol Biol       Date:  1968-05-14       Impact factor: 5.469

6.  N-Formylmethionine deformylase from Euglena gracilis.

Authors:  J N Aronson; J C Lugay
Journal:  Biochem Biophys Res Commun       Date:  1969-02-07       Impact factor: 3.575

7.  Amino acid acylases: proposed relation to metabolic recycling of methionine during protein biosynthesis.

Authors:  J C Lugay; J N Aronson
Journal:  Biochem Biophys Res Commun       Date:  1967-05-25       Impact factor: 3.575

8.  The structure-activity relations of synthetic peptides as chemotactic factors and inducers of lysosomal secretion for neutrophils.

Authors:  H J Showell; R J Freer; S H Zigmond; E Schiffmann; S Aswanikumar; B Corcoran; E L Becker
Journal:  J Exp Med       Date:  1976-05-01       Impact factor: 14.307
  8 in total
  1 in total

1.  Gut Microbiota and Metabolome Description of Antibiotic-Treated Neonates From Parturients With Intrauterine Infection.

Authors:  Huitao Li; Lei Fu; Xueyu Chen; Heng Xu; Qinlong Jing; Chuanzhong Yang; Zhengwei Wan; Yiran Chen
Journal:  Front Cell Infect Microbiol       Date:  2022-03-18       Impact factor: 5.293
  1 in total

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