Literature DB >> 518014

Application of electroimmunoassay to the study of plasma protein synthesis in cultured hepatocytes.

G Grieninger, J Pindyck, K M Hertzberg, M W Mosesson.   

Abstract

Electroimmunoassay has been applied to the study of plasma protein synthesis and secretion in liver cell cultures. The assay is performed on unconcentrated samples of culture medium containing the secreted plasma proteins and yields results within 2 hours. The characteristics of plasma protein production by the cultured hepatocytes coupled with the sensitivity of this assay permit the study of plasma protein in synthesis and its regulation by hormones and other agents without the routine use of radioisotopes.

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Year:  1979        PMID： 518014

Source DB:  PubMed          Journal:  Ann Clin Lab Sci        ISSN： 0091-7370            Impact factor:   1.256


  6 in total

1.  Effect of hepatocyte-stimulating factor and glucocorticoids on plasma fibronectin levels.

Authors:  D L Amrani; D Mauzy-Melitz; M W Mosesson
Journal:  Biochem J       Date:  1986-09-01       Impact factor: 3.857

2.  The effects of acute-phase inducers and dimethyl sulphoxide on delta-aminolaevulinate synthase activity in human HepG2 hepatoma cells.

Authors:  F Iwasa; S Sassa; A Kappas
Journal:  Biochem J       Date:  1989-04-15       Impact factor: 3.857

3.  Effects of dimethyl sulphoxide on the synthesis of plasma proteins in the human hepatoma HepG2. Induction of an acute-phase-like reaction.

Authors:  F Iwasa; R A Galbraith; S Sassa
Journal:  Biochem J       Date:  1988-08-01       Impact factor: 3.857

4.  Induction of reversible shock by Escherichia coli lipopolysaccharide in rats. Changes in serum and cell membrane parameters.

Authors:  M A Bosch; R García; R Pagani; M T Portolés; I Díaz-Laviada; S Abarca; M J Ainaga; C Risco; A M Municio
Journal:  Br J Exp Pathol       Date:  1988-12

5.  Hereditary tyrosinemia and the heme biosynthetic pathway. Profound inhibition of delta-aminolevulinic acid dehydratase activity by succinylacetone.

Authors:  S Sassa; A Kappas
Journal:  J Clin Invest       Date:  1983-03       Impact factor: 14.808

6.  Direct effect of insulin on the synthesis of specific plasma proteins: biphasic response of hepatocytes cultured in serum- and hormone-free medium.

Authors:  T J Liang; G Grieninger
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205
  6 in total

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