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Literature DB >> 5157727

Responses to pressor substances in conscious and anaesthetized cats.

Abstract

The blood pressure responses to intravenous injections of noradrenaline, tyramine and McN-A-343 have been determined in conscious cats and in cats under pentobarbitone sodium, alpha-chloralose, urethane or alpha-chloralose plus urethane anaesthesia. All four anaesthetic agents reduced the pressor responses, the reduction being most pronounced with urethane and least pronounced with alpha-chloralose. Pentobarbitone sodium exerted a greater inhibitory effect on the responses to McN-A-343 than on those to noradrenaline or tyramine.

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Year: 1971 PMID： 5157727 PMCID： PMC1665802 DOI： 10.1111/j.1476-5381.1971.tb07196.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

4 in total

Review 2. Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2: Cardiovascular system.

Authors: C A Maggi; A Meli
Journal: Experientia Date: 1986-03-15

3. Urethane and contraction of vascular smooth muscle.

Authors: B M Altura; J Weinberg
Journal: Br J Pharmacol Date: 1979-10 Impact factor: 8.739

4. An analysis of the effects of urethane on cardiovascular responsiveness to catecholamines in terms of its interference with Ca++ mobilization from both intra and extracellular pools.

Authors: C A Maggi; S Manzini; M Parlani; A Meli
Journal: Experientia Date: 1984-01-15

4 in total

Responses to pressor substances in conscious and anaesthetized cats.

1. An unusual type of sympathetic ganglionic stimulant.

2. Depression of autonomic ganglia by barbiturates.

3. Continuous blood pressure measurement in non-anaesthetized animals.

4. The effect of reserpine on the pressor responses to angiotensin in the conscious cat.

1. Unsuitability of urethane anesthetized rats for testing potential beta-adrenoreceptor blockers.

Review 2. Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2: Cardiovascular system.

3. Urethane and contraction of vascular smooth muscle.

4. An analysis of the effects of urethane on cardiovascular responsiveness to catecholamines in terms of its interference with Ca++ mobilization from both intra and extracellular pools.