Literature DB >> 3007197

Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2: Cardiovascular system.

C A Maggi, A Meli.   

Abstract

Urethane produces a level of surgical anesthesia characterized by preservation of a number of cardiovascular reflexes. When the proper route of administration is used, and the use of unnecessarily high doses is avoided, urethane anesthesia appears to be suitable for a number of investigations at cardiovascular level. However in certain types of studies involving pharmacological stimulation of peripheral adrenoceptors urethane affects markedly the magnitude of the response under study.

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Year:  1986        PMID： 3007197     DOI： 10.1007/bf01942510

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  55 in total

1.  URETHANE HYPERGLYCAEMIA AND HYPOTHALAMIC ACTIVATION.

Authors:  H REINERT
Journal:  Nature       Date:  1964-11-28       Impact factor: 49.962

2.  [Role of different types of afferent fibers in general circulatory reflexes of cutaneous origin].

Authors:  Y LAPORTE; P MONTASTRUC
Journal:  J Physiol (Paris)       Date:  1957-11

3.  Carotid-occlusion-pressor reflex: influence of existing mean arterial pressure, of anesthetics and of ganglionic- and adrenergic-blocking drugs.

Authors:  G PROCHNIK; G L MAISON; J W STUTZMAN
Journal:  Am J Physiol       Date:  1950-09

4.  Functional role of cardiac presynaptic alpha 2-adrenoreceptors in the bradycardia of alpha-adrenoreceptor agonists in pentobarbitone-and urethane-anaesthetized normotensive rats.

Authors:  A De Jonge; P N Santing; P B Timmermans; P A Van Zwieten
Journal:  J Auton Pharmacol       Date:  1982-06

5.  The effect of peripherally administered GABA on noradrenaline-induced reflex vagal bradycardia in urethane anaesthetized rats.

Authors:  C A Maggi; S Giuliani; A Meli
Journal:  Gen Pharmacol       Date:  1985

6.  Correlation between the inhibitory activities of calcium entry blockers on vascular smooth muscle constriction in vitro after K+-depolarisation and in vivo after alpha 2-adrenoceptor stimulation.

Authors:  J C van Meel; R Towart; S Kazda; P B Timmermans; P A van Zwieten
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1983-02       Impact factor: 3.000

7.  The effect of ethylurethane on hematocrit, blood pressure and plasma-glucose.

Authors:  C Van Der Meer; J A Versluys-Broers; H A Tuynman; V A Buur
Journal:  Arch Int Pharmacodyn Ther       Date:  1975-10

8.  Potentiation by naloxone of pressor reflexes.

Authors:  J L Montastruc; P Montastruc; F Morales-Olivas
Journal:  Br J Pharmacol       Date:  1981-09       Impact factor: 8.739

9.  An analysis of the effects of urethane on cardiovascular responsiveness to catecholamines in terms of its interference with Ca++ mobilization from both intra and extracellular pools.

Authors:  C A Maggi; S Manzini; M Parlani; A Meli
Journal:  Experientia       Date:  1984-01-15

Review 10.  Modulation of noradrenaline release through activation of presynaptic beta-adrenoreceptors.

Authors:  H Majewski
Journal:  J Auton Pharmacol       Date:  1983-03
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  44 in total

1.  Effects of common anesthetics on eye movement and electroretinogram.

Authors:  Govind Nair; Moon Kim; Tsukasa Nagaoka; Darin E Olson; Peter M Thulé; Machelle T Pardue; Timothy Q Duong
Journal:  Doc Ophthalmol       Date:  2011-04-26       Impact factor: 2.379

2.  Colorectal and cardiovascular effects of [Lys5,MeLeu9,Nle10]-NKA(4-10) in anesthetized macaques.

Authors:  Nadia M J Rupniak; Mary Katofiasc; Edward C Burgard; Karl B Thor
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2018-06-01       Impact factor: 3.000

3.  Increase in plasma ACTH induced by urethane is not a consequence of hyperosmolality.

Authors:  Dmitry V Zaretsky; Andrei I Molosh; Maria V Zaretskaia; Daniel E Rusyniak; Joseph A DiMicco
Journal:  Neurosci Lett       Date:  2010-05-12       Impact factor: 3.046

4.  In vivo performance of a microelectrode neural probe with integrated drug delivery.

Authors:  Pratik Rohatgi; Nicholas B Langhals; Daryl R Kipke; Parag G Patil
Journal:  Neurosurg Focus       Date:  2009-07       Impact factor: 4.047

5.  Effects of urethane on reflex activity of lower urinary tract in decerebrate unanesthetized rats.

Authors:  Mitsuharu Yoshiyama; James R Roppolo; Masayuki Takeda; William C de Groat
Journal:  Am J Physiol Renal Physiol       Date:  2012-11-28

6.  Influence of ACTH-(1-24) on free radical levels in the blood of haemorrhage-shocked rats: direct ex vivo detection by electron spin resonance spectrometry.

Authors:  S Guarini; C Bazzani; G M Ricigliano; A Bini; A Tomasi; A Bertolini
Journal:  Br J Pharmacol       Date:  1996-09       Impact factor: 8.739

7.  Spontaneous respiratory plasticity following unilateral high cervical spinal cord injury in behaving rats.

Authors:  Tatiana Bezdudnaya; Kristiina M Hormigo; Vitaliy Marchenko; Michael A Lane
Journal:  Exp Neurol       Date:  2018-03-26       Impact factor: 5.330

8.  Dexmedetomidine-induced decrease in cerebral blood flow is attenuated by verapamil in rats: a laser Doppler study.

Authors:  F Bari; G Horváth; G Benedek
Journal:  Can J Anaesth       Date:  1993-08       Impact factor: 5.063

9.  Intracranial pressure and brain redox balance in rabbits.

Authors:  B Bissonnette; P E Bickler; G A Gregory; J W Severinghaus
Journal:  Can J Anaesth       Date:  1991-07       Impact factor: 5.063

10.  Differences in cardiovascular responses to peripherally administered GABA as influenced by basal conditions and type of anaesthesia.

Authors:  S Giuliani; C A Maggi; A Meli
Journal:  Br J Pharmacol       Date:  1986-07       Impact factor: 8.739
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