Literature DB >> 5142268

Target cell destruction in vitro by concanavalin A-stimulated lymphoid cells.

H J Schwartz, F Wilson.   

Abstract

Guinea pig lymphoid cells obtained from lymph nodes and spleens of nonimmune animals are cytotoxic for mouse L-cell fibroblasts on incubation with concanavalin A. This effect is blocked by methyl-alpha-D-mannoside. The results indicate that this effect may be due to the release of a lymphotoxin by the concanavalin A-stimulated lymphocytes.

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Year:  1971        PMID: 5142268      PMCID: PMC2047574     

Source DB:  PubMed          Journal:  Am J Pathol        ISSN: 0002-9440            Impact factor:   4.307


  14 in total

1.  Concanavalin A-induced release of skin-reactive factor from lymphoid cells.

Authors:  H J Schwartz; M A Leon; R P Pelley
Journal:  J Immunol       Date:  1970-01       Impact factor: 5.422

2.  Immunosuppressive activity of concanavalin A.

Authors:  H Markowitz; D A Person; G L Gitnick; R E Ritts
Journal:  Science       Date:  1969-01-31       Impact factor: 47.728

3.  Lymphocyte cytotoxicity in vitro: activation and release of a cytotoxic factor.

Authors:  G A Granger; T W Williams
Journal:  Nature       Date:  1968-06-29       Impact factor: 49.962

4.  Release of skin reactive factor from guinea-pig lymphocytes by mitogens.

Authors:  E Pick; J Krejcí; J L Turk
Journal:  Nature       Date:  1970-01-17       Impact factor: 49.962

5.  Inhibition of cytotoxicity of lymphocytes by concanavalin A in vitro.

Authors:  P Perlmann; H Nilsson; M A Leon
Journal:  Science       Date:  1970-05-29       Impact factor: 47.728

6.  Inhibition of delayed hypersensitivity to tuberculin by concanavalin A.

Authors:  M A Leon; H J Schwartz
Journal:  Proc Soc Exp Biol Med       Date:  1969-07

7.  Desensitization to delayed hypersensitivity reactions. With special reference to the requirement for an immunogenic molecule.

Authors:  S F Schlossman; H Levine
Journal:  J Immunol       Date:  1967-07       Impact factor: 5.422

8.  Cytotoxic effect of lymphocyte-antigen interaction in delayed hypersensitivity.

Authors:  N H Ruddle; B H Waksman
Journal:  Science       Date:  1967-09-01       Impact factor: 47.728

9.  Concanavalin A reaction with human normal immunoglobulin G and myeloma immunoglobulin G.

Authors:  M A Leon
Journal:  Science       Date:  1967-12-08       Impact factor: 47.728

10.  Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. 3. Analysis of mechanism.

Authors:  N H Ruddle; B H Waksman
Journal:  J Exp Med       Date:  1968-12-01       Impact factor: 14.307

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  5 in total

1.  The detection and identification of subpopulations of circulating human lymphocytes, monocytes and neutrophils capable of effecting a mitogen-induced cell-mediated cytotoxic reaction towards erythrocytes of various species.

Authors:  M Cortens; S Sklar; M Richter
Journal:  Immunology       Date:  1980-11       Impact factor: 7.397

2.  Lectin-dependent neutrophil-mediated cytotoxicity. I. Characteristics.

Authors:  L Simchowitz; P H Schur
Journal:  Immunology       Date:  1976-08       Impact factor: 7.397

3.  Cytotoxicity of concanavalin A-activated hamster lymphocytes.

Authors:  S B Singh; S S Tevethia
Journal:  Infect Immun       Date:  1973-01       Impact factor: 3.441

4.  Cell-mediated immune responses in vitro. I. Suppression of the generation of cytotoxic lymphocytes by concanavalin A and concanavalin A-activated spleen cells.

Authors:  D L Peavy; C W Pierce
Journal:  J Exp Med       Date:  1974-08-01       Impact factor: 14.307

5.  Biological expressions of lymphocyte activation : I. Effects of phytomitogens on antibody synthesis in vitro.

Authors:  R R Rich; C W Pierce
Journal:  J Exp Med       Date:  1973-01-31       Impact factor: 14.307

  5 in total

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