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Literature DB >> 5133731

Autoimmune murine thyroiditis relation to histocompatibility (H-2) type.

Abstract

Immunization of 33 inbred strains of mice with thyroid extract emulsified in complete Freund's adjuvant showed differences in both thyroid autoantibody response and autoimmune thyroid damage, related to the histocompatibility (H-2) type of the strain. Congenic mice of the same H-2 type exhibited the same pattern of antibody response and thyroiditis, regardless of the strain's genetic background, thus showing a close relation between histocompatibility determinants and autoimmunity.

Entities: Disease Gene Species

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Year: 1971 PMID： 5133731 DOI： 10.1126/science.174.4014.1137

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

97 in total

Review 1. Thyroglobulin as autoantigen: structure-function relationships.

Authors: M Vali; N R Rose; P Caturegli
Journal: Rev Endocr Metab Disord Date: 2000-01 Impact factor: 6.514

2. Transplantation antigens in Crohn's disease: Linkage of associated ankylosing spondylitis with HL-Aw27.

Authors: A S Russell; J S Percy; J Schlaut; V E Sartor; J M Goodhart; R W Sherbaniuk; E G Kidd
Journal: Am J Dig Dis Date: 1975-04

3. Fine epitope mapping within the pathogenic thyroglobulin peptide 2340-2359: minimal epitopes retaining antigenicity across various MHC haplotypes are not necessarily immunogenic.

Authors: Aikaterini Hatzioannou; Maria Alevizaki; George Carayanniotis; Peggy Lymberi
Journal: Immunology Date: 2012-03 Impact factor: 7.397

Autoimmune murine thyroiditis relation to histocompatibility (H-2) type.

Review 1. Thyroglobulin as autoantigen: structure-function relationships.

2. Transplantation antigens in Crohn's disease: Linkage of associated ankylosing spondylitis with HL-Aw27.

3. Fine epitope mapping within the pathogenic thyroglobulin peptide 2340-2359: minimal epitopes retaining antigenicity across various MHC haplotypes are not necessarily immunogenic.

4. An MHC-linked locus modulates thymic differentiation of CD4+CD25+Foxp3+ regulatory T lymphocytes.

5. High salt intake does not exacerbate murine autoimmune thyroiditis.

6. Thyroid function in mice with experimental autoimmune thyroiditis.

7. The IgG2a antibody response to thyroglobulin is linked to the Igh locus in mouse.

Review 8. Autoimmune thyroiditis research at Johns Hopkins University.

9. Sex and strain variability in the rat hypothalamo-pituitary-adrenal (HPA) axis function.

10. Autoimmune hypophysitis of SJL mice: clinical insights from a new animal model.