Literature DB >> 512356

Potential risk of salivary-mediated viral hepatitis type B transmission from oral exposure to fomites.

M T Osterholm, B J Max, M Hanson, H F Polesky.   

Abstract

Twelve grade school and junior high school students had oral exposures to hepatitis B surface antigen (HBsAg) positive saliva via contact with contaminated musical instruments. The 12 exposed students and 18 students who served as age and sex matched controls were tested for the presence of HBsAg and antibody to the hepatitis surface antigen (anti-HBs) at 2 weeks, 8 weeks and 6 months after exposure. All students were negative for HBsAg and anti-HBs on all dates tested and reported no illness during that time suggestive of viral hepatitis. There was no evidence of viral hepatitis, type B transmission from the exposure. The students probably experienced the maximum possible oral exposure from direct or fomites contact, since there was no cleaning of the musical instruments between use by the students and teacher. Based on these results, the risk of transmission of viral hepatitis, type B from oral contact with fomites is unlikely.

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Year:  1979        PMID: 512356      PMCID: PMC2130173          DOI: 10.1017/s0022172400026322

Source DB:  PubMed          Journal:  J Hyg (Lond)        ISSN: 0022-1724


  12 in total

1.  Hepatitis B surface antigen in saliva of HB-SAg carriers.

Authors:  S V Feinman; O Krassnitski; J C Sinclair; D M Wrobel; B Berris
Journal:  J Lab Clin Med       Date:  1975-06

2.  Transmission of hepatitis B to chimpanzees by hepatitis B surface antigen-positive saliva and semen.

Authors:  H J Alter; R H Purcell; J L Gerin; W T London; P M Kaplan; V J McAuliffe; J Wagner; P V Holland
Journal:  Infect Immun       Date:  1977-06       Impact factor: 3.441

3.  Hepatitis-B antigen in saliva and semen.

Authors:  J Heathcote; C H Cameron; D S Dane
Journal:  Lancet       Date:  1974-01-19       Impact factor: 79.321

4.  Hepatitis B antigen (HB-Ag, Australia antigen) in mixed saliva of patients with HB antigenemia.

Authors:  G S Kistler; W Sonnabend; U Krech
Journal:  Pathol Microbiol (Basel)       Date:  1973

5.  Hepatitis B antigen in saliva and mouth washings.

Authors:  R Ward; P Borchert; A Wright; E Kline
Journal:  Lancet       Date:  1972-10-07       Impact factor: 79.321

6.  Biochemical characterization of Australia antigen. Evidence for defective particles of hepatitis B virus.

Authors:  J L Gerin; E C Ford; R H Purcell
Journal:  Am J Pathol       Date:  1975-12       Impact factor: 4.307

7.  Hepatitis B antigen in saliva, urine, and stool.

Authors:  G R Irwin; A M Allen; W H Bancroft; J J Karwacki; H L Brown; R H Pinkerton; M Willhight; F H Top
Journal:  Infect Immun       Date:  1975-01       Impact factor: 3.441

8.  Hepatitis B subunit vaccine: a preliminary report of safety and efficacy tests in chimpanzees.

Authors:  R H Purcell; J L Gerin
Journal:  Am J Med Sci       Date:  1975 Sep-Oct       Impact factor: 2.378

9.  Transmission of hepatitis B virus to gibbons by exposure to human saliva containing hepatitis B surface antigen.

Authors:  W H Bancroft; R Snitbhan; R M Scott; M Tingpalapong; W T Watson; P Tanticharoenyos; J J Karwacki; S Srimarut
Journal:  J Infect Dis       Date:  1977-01       Impact factor: 5.226

10.  Detection of e antigen and antibody: correlations with hapatitis B surface and hepatitis B core antigens, liver disease, and outcome in hepatitis B infections.

Authors:  C G Trepo; L O Magnius; R A Schaefer; A M Prince
Journal:  Gastroenterology       Date:  1976-11       Impact factor: 22.682

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  1 in total

1.  Comparison of surface sampling methods for virus recovery from fomites.

Authors:  Timothy R Julian; Francisco J Tamayo; James O Leckie; Alexandria B Boehm
Journal:  Appl Environ Microbiol       Date:  2011-08-05       Impact factor: 4.792

  1 in total

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