| Literature DB >> 1169272 |
S V Feinman, O Krassnitski, J C Sinclair, D M Wrobel, B Berris.
Abstract
Two hundred and twelve saliva specimens of HB-SAg carriers were tested for HB-SAg by crossover immunoelectrophoresis (CIEP) and radioimmunoassay (RIA) after concentration, between April 1971 and September 1973. They were divided into 3 groups (A, B, and C). CIEP detected HG-SAg in 6 per cent in Group A (66 specimens) and in 12 percent in Group B (87 specimens), and in 78 per cent in Group C. Different methods of preparation and concentration of saliva specimens were discussed. The positive results by RIA were confirmed by a blocking test with rabbit HB-SAg antiserum. Intermittent presence of HB-SAg in repeated saliva specimens from individual carriers was found. Infected saliva of HB-SAg carriers may be of importance in transmission of hepatitis B infection.Entities:
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Year: 1975 PMID: 1169272
Source DB: PubMed Journal: J Lab Clin Med ISSN: 0022-2143