Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Histochemical detection of the enzyme deficiency in blood films in Wolman's disease.

Literature DB >> 5118828

Histochemical detection of the enzyme deficiency in blood films in Wolman's disease.

Abstract

The clinical diagnosis of Wolman's disease (acid esterase deficiency) can be confirmed by a histochemical staining method using blood films. Acid esterase activity is found normally in lymphocytes, but in Wolman's disease only a very low level of activity can be detected. An intermediate level of activity was demonstrated in heterozygotes. The method may also be applicable in the prenatal detection of the disease.

Entities: Disease

Mesh：

Substances：
Esterases

Year: 1971 PMID： 5118828 PMCID： PMC477106 DOI： 10.1136/jcp.24.7.617

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

10 in total

1. WOLMAN'S DISEASE: THREE NEW PATIENTS WITH A RECENTLY DESCRIBED LIPIDOSIS.

Authors: A C CROCKER; G F VAWTER; E B NEUHAUSER; A ROSOWSKY
Journal: Pediatrics Date: 1965-04 Impact factor: 7.124

2. Primary familial xanthomatosis with involvement and calcification of the adrenals. Report of two more cases in siblings of a previously described infant.

Authors: M WOLMAN; V V STERK; S GATT; M FRENKEL
Journal: Pediatrics Date: 1961-11 Impact factor: 7.124

3. Generalized xanthomatosis with calcified adrenals.

Authors: A ABRAMOV; S SCHORR; M WOLMAN
Journal: AMA J Dis Child Date: 1956-03

Review 4. The histochemical evaluation of the glycogen storage diseases. A review of techniques and their limitations.

Authors: B D Lake
Journal: Histochem J Date: 1970-09

5. Hepatic cholesterol ester storage disease, a familial disorder. I. Clinical aspects.

Authors: L Schiff; W K Schubert; A J McAdams; E L Spiegel; J F O'Donnell
Journal: Am J Med Date: 1968-04 Impact factor: 4.965

6. Wolman's disease: deficiency of E600-resistant acid esterase activity with storage of lipids in lysosomes.

Authors: B D Lake; A D Patrick
Journal: J Pediatr Date: 1970-02 Impact factor: 4.406

7. Wolman's disease--an unusual presentation.

Authors: R L Orme; F S Brimblecombe
Journal: Proc R Soc Med Date: 1970-05

8. Deficiency of acid esterase activity in Wolman's disease.

Authors: E P Young; A D Patrick
Journal: Arch Dis Child Date: 1970-10 Impact factor: 3.791

9. Deficiency of an acid lipase in Wolman's disease.

Authors: A D Patrick; B D Lake
Journal: Nature Date: 1969-06-14 Impact factor: 49.962

10. Wolman's disease: the first case in Japan.

Authors: T Konno; M Fujii; T Watanuki; K Koizumi
Journal: Tohoku J Exp Med Date: 1966-12 Impact factor: 1.848

10 in total

8 in total

1. The in vivo effects of quartz on rat thoracic lymph nodes.

Authors: S Klempman; K Miller
Journal: Br J Exp Pathol Date: 1977-10

2. Immunocytochemical analysis of HLA class II (DR) antigens in liver disease in man.

Authors: C Barbatis; P Kelly; J Greveson; A Heryet; J O McGee
Journal: J Clin Pathol Date: 1987-08 Impact factor: 3.411

3. Blood film examination for vacuolated lymphocytes in the diagnosis of metabolic disorders; retrospective experience of more than 2,500 cases from a single centre.

Authors: G Anderson; V V Smith; M Malone; N J Sebire
Journal: J Clin Pathol Date: 2005-12 Impact factor: 3.411

4. Lymphocytes bearing Fc gamma receptors in rheumatoid arthritis. I. An increased subpopulation of cells in rheumatoid arthritis detected with Facb rosettes.

Authors: N D Hall; V R Winrow; P A Bacon
Journal: Ann Rheum Dis Date: 1980-12 Impact factor: 19.103

8. Studies of lymphocytes in rheumatoid arthritis. I. Uptake of 125I-heat aggregated human IgG by Fc-receptor bearing lymphocytes.

Authors: P H Wooley; G S Panayi
Journal: Ann Rheum Dis Date: 1978-08 Impact factor: 19.103