Literature DB >> 51055

A revised boron-neutron capture therapy for malignant brain tumors. II. Interim clinical result with the patients excluding previous treatments.

H Hatanaka.   

Abstract

Fifteen brain tumor patients were treated with slow neutron. It proved to extend life span of terminal glioblastoma patients irresponsive to Co-60, to 2 years, but quality of survival is poor due to complications of previous treatments. Two glioblastoma patients excluding other treatments, the only genuine Boron-neutron capture therapy cases, have been living for 39+ and 34+ months working full-scale without neurological deficit.

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Year:  1975        PMID: 51055     DOI: 10.1007/bf00314601

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  8 in total

1.  Effect of thermal neutrons on central nervous system. Apparent tolerance of central nervous system structures in man.

Authors:  L E FARR; W G CALVO; W HAYMAKER; S W LIPPINCOTT; Y L YAMAMOTO; E E STICKLEY
Journal:  Arch Neurol       Date:  1961-03

2.  Glioblastoma multiforme: a clinical survey.

Authors:  J G ROTH; A R ELVIDGE
Journal:  J Neurosurg       Date:  1960-07       Impact factor: 5.115

Review 3.  Proceedings: A reassessment of neutron capture therapy in the treatment of cerebral gliomas.

Authors:  G L Brownell; B W Murray; W H Sweet; G R Wellum; A H Soloway
Journal:  Proc Natl Cancer Conf       Date:  1972

4.  A revised boron-neutron capture therapy for malignant brain tumours. I. Experience on terminally ill patients after Co-60 radiotherapy.

Authors:  H Hatanaka; K Sano
Journal:  Z Neurol       Date:  1973

5.  The relative significance of factors affecting postoperative survival in astrocytomas, grades 3 and 4.

Authors:  B Weir
Journal:  J Neurosurg       Date:  1973-04       Impact factor: 5.115

6.  "Epithermal" neutron beam isodose charts in a phantom head.

Authors:  R G Fairchild
Journal:  Radiology       Date:  1965-09       Impact factor: 11.105

7.  Effect of neutron capture irradiation upon malignant brain tumors in mice.

Authors:  W Entzian; A H Soloway; R Raju; W H Sweet; G L Brownell
Journal:  Acta Radiol Ther Phys Biol       Date:  1966

8.  Electron microscopic study on the response of the normal canine brain to boron-neutron capture therapy.

Authors:  S F Al-Samarrai; A Takeuchi; H Hatanaka
Journal:  Gan       Date:  1975-12
  8 in total
  11 in total

1.  Intracavitary moderator balloon combined with (252)Cf brachytherapy and boron neutron capture therapy, improving dosimetry in brain tumour and infiltrations.

Authors:  S F Brandão; T P R Campos
Journal:  Br J Radiol       Date:  2015-04-30       Impact factor: 3.039

Review 2.  Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era.

Authors:  Minoru Suzuki
Journal:  Int J Clin Oncol       Date:  2019-06-05       Impact factor: 3.402

3.  Liposomes as drug delivery vehicles for boron agents.

Authors:  M F Hawthorne; K Shelly
Journal:  J Neurooncol       Date:  1997-05       Impact factor: 4.130

4.  Determining a methodology of dosimetric quality assurance for commercially available accelerator-based boron neutron capture therapy system.

Authors:  Katsumi Hirose; Takahiro Kato; Takaomi Harada; Tomoaki Motoyanagi; Hiroki Tanaka; Akihiko Takeuchi; Ryohei Kato; Shinya Komori; Yuhei Yamazaki; Kazuhiro Arai; Noriyuki Kadoya; Mariko Sato; Yoshihiro Takai
Journal:  J Radiat Res       Date:  2022-07-19       Impact factor: 2.438

5.  Boron-neutron capture therapy in relation to immunotherapy.

Authors:  H Hatanaka; K Amano; S Kamano; H Fankhauser; T Hanamura; K Sano
Journal:  Acta Neurochir (Wien)       Date:  1978       Impact factor: 2.216

6.  Model studies directed toward the boron neutron-capture therapy of cancer: boron delivery to murine tumors with liposomes.

Authors:  K Shelly; D A Feakes; M F Hawthorne; P G Schmidt; T A Krisch; W F Bauer
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-01       Impact factor: 11.205

7.  Cerebral space-occupying cysts following radiation and chemotherapy of malignant gliomas.

Authors:  D Volc; K Jellinger; H Flament; F Böck; J Klumair
Journal:  Acta Neurochir (Wien)       Date:  1981       Impact factor: 2.216

8.  Uptake and metabolism of boronophenylalanine in human uveal melanoma cells in culture Relevance to boron neutron capture therapy of cancer cells.

Authors:  R Belkhou; J C Abbé; P Pham; N Jasner; J Sahel; H Dreyfus; M Moutaouakkil; R Massarelli
Journal:  Amino Acids       Date:  1995-06       Impact factor: 3.520

9.  Human Serum Albumin Labelling with a New BODIPY Dye Having a Large Stokes Shift.

Authors:  Valeria I Raskolupova; Tatyana V Popova; Olga D Zakharova; Anastasia E Nikotina; Tatyana V Abramova; Vladimir N Silnikov
Journal:  Molecules       Date:  2021-05-03       Impact factor: 4.411

10.  Early clinical experience utilizing scintillator with optical fiber (SOF) detector in clinical boron neutron capture therapy: its issues and solutions.

Authors:  Masayori Ishikawa; Tetsuya Yamamoto; Akira Matsumura; Junichi Hiratsuka; Shin-Ichi Miyatake; Itsuro Kato; Yoshinori Sakurai; Hiroaki Kumada; Shubhechha J Shrestha; Koji Ono
Journal:  Radiat Oncol       Date:  2016-08-09       Impact factor: 3.481

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