| Literature DB >> 5098960 |
I M Diab, D X Freedman, L J Roth.
Abstract
Intravenous administration of [(3)H]lysergic acid diethylamide(LSD) to rats resulted in accumulation of the drug in the brain within 15 minutes. Autoradiographic methods were used to differentiate free and bound [(3)H]LSD in brain tissue. Free [(3)H]LSD was generally distributed in the pituitary and pineal glands, cerebellum, hippocampus,and choroid plexus. Bound [(3)H]LSD was localized in neurons of the cortex, caudate nucleus, midbrain, and medulla,as well as in choroid plexus epithelium.Entities:
Mesh：
Substances：
Year: 1971 PMID： 5098960 DOI： 10.1126/science.173.4001.1022
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728