Literature DB >> 5091166

Further studies on the effect of ageing on beta-adrenoceptor activity of rat aorta.

J H Fleisch.   

Abstract

beta-Adrenoceptor activity of rat thoracic aorta decreased with the increasing age of the animal. The ability of aortas to relax to isoprenaline was completely lost when rats were 3-6 months old, depending on the source and strain of animals. NaNO(2), however, completely relaxed aortic tissue from animals of all ages tested.

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Year:  1971        PMID： 5091166      PMCID： PMC1667170          DOI： 10.1111/j.1476-5381.1971.tb07115.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  2 in total

1.  Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs.

Authors:  R F FURCHGOTT; S BHADRAKOM
Journal:  J Pharmacol Exp Ther       Date:  1953-06       Impact factor: 4.030

2.  Beta-receptor activity in aorta; variations with age and species.

Authors:  J H Fleisch; H M Maling; B B Brodie
Journal:  Circ Res       Date:  1970-02       Impact factor: 17.367
  2 in total
  8 in total

1.  The effect of age on -adrenoceptor activity in tracheal smooth muscle.

Authors:  G Aberg; G Adler
Journal:  Br J Pharmacol       Date:  1973-01       Impact factor: 8.739

Review 2.  Age-related changes in vascular smooth muscle and endothelium.

Authors:  Y Dohi; M Kojima; K Sato; T F Lüscher
Journal:  Drugs Aging       Date:  1995-10       Impact factor: 3.923

3.  Decreased vascular sensitivity to histamine during aging.

Authors:  C Brink; P G Duncan; J S Douglas
Journal:  Agents Actions       Date:  1984-01

4.  Age-related alterations in alpha 1- and beta-adrenoceptors mediated responsiveness of rat aorta.

Authors:  L Hyland; P Warnock; J R Docherty
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-01       Impact factor: 3.000

5.  Effects of histamine and the histamine antagonists mepyramine and cimetidine on human coronary arteries in vitro.

Authors:  T Godfraind; R C Miller
Journal:  Br J Pharmacol       Date:  1983-08       Impact factor: 8.739

6.  Reduction with age in the relaxation to beta-adrenoceptor agonists and other vasodilators in rat aorta.

Authors:  R Sawyer; J R Docherty
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-07       Impact factor: 3.000

7.  Age-related changes in the response of rabbit isolated aortae to vasoactive agents.

Authors:  S Hayashi; N Toda
Journal:  Br J Pharmacol       Date:  1978-10       Impact factor: 8.739

8.  Biochemical and molecular aspects of vascular adrenergic regulation of blood pressure in the elderly.

Authors:  William E Schutzer; Scott L Mader
Journal:  Int J Hypertens       Date:  2011-09-22       Impact factor: 2.420
  8 in total

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