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Literature DB >> 508508

Comparison of the pharmacokinetics of metronidazole in healthy female volunteers following either a single oral or intravenous dose.

G W Houghton, P S Thorne, J Smith, R Templeton, J Collier.

Abstract

Entities: Chemical

Mesh：

Substances：
Metronidazole

Year: 1979 PMID： 508508 PMCID： PMC1429835 DOI： 10.1111/j.1365-2125.1979.tb04715.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

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6 in total

1. Treatment with metronidazole of three patients with serious infections due to Bacteroides fragilis.

Authors: H R Ingham; G E Rich; J B Selkon; J H Hale; C M Roxby; M J Betty; R W Johnson; P R Uldall
Journal: J Antimicrob Chemother Date: 1975-06 Impact factor: 5.790

2. The pharmacokinetics of metronidazole and tinidazole in man.

Authors: P G Welling; A M Monro
Journal: Arzneimittelforschung Date: 1972-12

3. The isolation and identification of the urinary oxidative metabolites of metronidazole in man.

Authors: J E Stambaugh; L G Feo; R W Manthei
Journal: J Pharmacol Exp Ther Date: 1968-06 Impact factor: 4.030

4. Determination of metronidazole and its two major metabolites in biological fluids by high pressure liquid chromatography.

Authors: A Gulaid; G W Houghton; O R Lewellen; J Smith; P S Thorne
Journal: Br J Clin Pharmacol Date: 1978-11 Impact factor: 4.335

5. Comparative pharmacokinetic studies of ornidazole and metronidazole in man.

Authors: D E Schwartz; F Jeunet
Journal: Chemotherapy Date: 1976 Impact factor: 2.544

6. Standardized antimicrobial disc susceptibility testing of anaerobic bacteria. I. Susceptibility of Bacteroides fragilis to tetracycline.

Authors: V L Sutter; Y Y Kwok; S M Finegold
Journal: Appl Microbiol Date: 1972-02

6 in total

27 in total

1. In vitro activities of clindamycin, imipenem, metronidazole, and piperacillin-tazobactam against susceptible and resistant isolates of Bacteroides fragilis evaluated by kill kinetics.

Authors: Reiner Schaumann; Matthias Funke; Eva Janssen; Arne C Rodloff
Journal: Antimicrob Agents Chemother Date: 2012-03-19 Impact factor: 5.191

Comparison of the pharmacokinetics of metronidazole in healthy female volunteers following either a single oral or intravenous dose.

1. Treatment with metronidazole of three patients with serious infections due to Bacteroides fragilis.

2. The pharmacokinetics of metronidazole and tinidazole in man.

3. The isolation and identification of the urinary oxidative metabolites of metronidazole in man.

4. Determination of metronidazole and its two major metabolites in biological fluids by high pressure liquid chromatography.

5. Comparative pharmacokinetic studies of ornidazole and metronidazole in man.

6. Standardized antimicrobial disc susceptibility testing of anaerobic bacteria. I. Susceptibility of Bacteroides fragilis to tetracycline.

1. In vitro activities of clindamycin, imipenem, metronidazole, and piperacillin-tazobactam against susceptible and resistant isolates of Bacteroides fragilis evaluated by kill kinetics.

Review 2. Clinical pharmacokinetics of metronidazole.

3. Intravenous metronidazole in the newborn.

4. Comparative pharmacokinetics of metronidazole and tinidazole as influenced by administration route.

5. Influence of dose and route of administration on disposition of metronidazole and its major metabolites.

6. Disposition of oral metronidazole in hepatic cirrhosis and in hepatosplenic schistosomiasis.

7. The penetration of metronidazole into synovial fluid.

Review 8. Metronidazole. A therapeutic review and update.

9. Disposition and removal of metronidazole in patients undergoing haemodialysis.

Review 10. Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives.