Literature DB >> 5063203

Tenuazonic acid, a toxic produced by Alternaria alternata.

R A Meronuck, J A Steele, C J Mirocha, C M Christensen.   

Abstract

Fifty-seven of 87 isolates of Alternaria alternata (Fr) Keissler grown on autoclaved, moist corn-rice substrate and fed to rats were lethal. The major toxin produced was isolated and characterized as tenuazonic acid. Twenty of 23 toxigenic Alternaria isolates examined produced tenuazonic acid. No tenuazonic acid could be detected in either of the field samples of sorghum or blackeyed peas, which were heavily invaded by Alternaria.

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Year:  1972        PMID： 5063203      PMCID： PMC380395          DOI： 10.1128/am.23.3.613-617.1972

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  7 in total

1.  Studies in the biochemistry of micro-organisms. 106. Metabolites of Alternaria tenuis auct.: the structure of tenuazonic acid.

Authors:  C E STICKINGS
Journal:  Biochem J       Date:  1959-06       Impact factor: 3.857

2.  Studies in the biochemistry of micro-organisms. 103. Metabolites of Alternaria tenuis auct; culture filtrate products.

Authors:  T ROSETT; R H SANKHALA; C E STICKINGS; M E TAYLOR; R THOMAS
Journal:  Biochem J       Date:  1957-11       Impact factor: 3.857

3.  Dose-response characteristics of aflatoxin B1 carcinogenesis in the rat.

Authors:  G N Wogan; P M Newberne
Journal:  Cancer Res       Date:  1967-12       Impact factor: 12.701

4.  Mycotoxicosis: toxicity to chicks of Alternaria longipes isolated from tobacco.

Authors:  B Doupnik; E K Sobers
Journal:  Appl Microbiol       Date:  1968-10

5.  Data on susceptibility to mycotoxins of day-old goslings.

Authors:  M Palyusik; I Szép; F Szöke
Journal:  Acta Vet Acad Sci Hung       Date:  1968

6.  Toxic effects of the sodium and the N,N'-dibenzylethylenediamine salts of tenuazonic acid (NSC-525816 and NSC-82260).

Authors:  E R Smith; T N Fredrickson; Z Hadidian
Journal:  Cancer Chemother Rep       Date:  1968-09

7.  Discovery of inhibitory activity of tenuazonic acid for growth of human adenocarcinoma-1.

Authors:  E A Kaczka; C O Gitterman; E L Dulaney; M C Smith; D Hendlin; H B Woodruff; K Folkers
Journal:  Biochem Biophys Res Commun       Date:  1964       Impact factor: 3.575
  7 in total
  14 in total

1.  Effect of substrate on metabolite production of Alternaria alternata.

Authors:  R Burroughs; L M Seitz; D B Sauer; H E Mohr
Journal:  Appl Environ Microbiol       Date:  1976-05       Impact factor: 4.792

2.  Assessing the mycotoxigenic threat of necrotrophic pathogens of wheat.

Authors:  Peter S Solomon
Journal:  Mycotoxin Res       Date:  2011-08-12       Impact factor: 3.833

3.  [Metabolic products of microorganisms. 3 lipomycins. I. Isolation, characterization and first studies of the structure and the mechanism of action].

Authors:  B Kunze; K Schabacher; H Zähner; A Zeeck
Journal:  Arch Mikrobiol       Date:  1972

4.  DFT study of the Lewis acid mediated synthesis of 3-acyltetramic acids.

Authors:  Hannes Mikula; Dennis Svatunek; Philipp Skrinjar; Ernst Horkel; Christian Hametner; Johannes Fröhlich
Journal:  J Mol Model       Date:  2014-05-03       Impact factor: 1.810

5.  Cyclopiazonic acid production by aflatoxigenic and non-aflatoxigenic strains of Aspergillus flavus.

Authors:  R T Gallagher; J L Richard; H M Stahr; R J Cole
Journal:  Mycopathologia       Date:  1978-12-29       Impact factor: 2.574

6.  Diverse polyketides from the marine endophytic Alternaria sp. LV52: Structure determination and cytotoxic activities.

Authors:  Manar M Mahmoud; Ahmed S Abdel-Razek; Hesham S M Soliman; Larissa V Ponomareva; Jon S Thorson; Khaled A Shaaban; Mohamed Shaaban
Journal:  Biotechnol Rep (Amst)       Date:  2021-05-24

7.  Mycotoxin production by some IndianAlternaria species.

Authors:  K S Bilgrami; A A Ansari; A K Sinha; A K Shrivastava; K K Sinha
Journal:  Mycotoxin Res       Date:  1994-03       Impact factor: 3.833

8.  Effect of water activity and temperature on mycotoxin production by Alternaria alternata in culture and on wheat grain.

Authors:  N Magan; G R Cayley; J Lacey
Journal:  Appl Environ Microbiol       Date:  1984-05       Impact factor: 4.792

9.  Toxins of molds from decaying tomato fruit.

Authors:  J Harwig; P M Scott; D R Stoltz; B J Blanchfield
Journal:  Appl Environ Microbiol       Date:  1979-08       Impact factor: 4.792

10.  Tenuazonic acid production by Alternaria alternata and Alternaria tenuissima isolated from cotton.

Authors:  N D Davis; U L Diener; G Morgan-Jones
Journal:  Appl Environ Microbiol       Date:  1977-08       Impact factor: 4.792
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