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Literature DB >> 5011243

Effect of D-cycloserine on transformation in group H streptococcus, strain Challis.

Abstract

d-Cycloserine (d-CS), a selective inhibitor of bacterial cell wall biosynthesis, inhibited transformation in group H streptococcus, strain Challis, by preventing the development of the competent state. The incubation of strain Challis cells with d-CS resulted in the production of a substance which inhibited the action of competence factor on these cells. d-CS had an enhancing effect on transformation when deoxyribonucleic acid uptake or phenotypic expression was allowed to occur in its presence.

Entities: Chemical

Mesh：

Substances：

Year: 1972 PMID： 5011243 PMCID： PMC247321 DOI： 10.1128/jb.109.3.1014-1019.1972

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

11 in total

1. BIOCHEMICAL ASPECTS OF COMPETENCE IN THE BACILLUS SUBTILIS TRANSFORMATION SYSTEM. I. CHEMICAL COMPOSITION OF CELL WALLS.

Authors: F E YOUNG; J SPIZIZEN; I P CRAWFORD
Journal: J Biol Chem Date: 1963-09 Impact factor: 5.157

2. THE EFFECT OF ENVIRONMENTAL FACTORS ON TRANSFORMABILITY OF A STREPTOCOCCUS.

Authors: R PAKULA; J CYBULSKA; W WALCZAK
Journal: Acta Microbiol Pol (1952) Date: 1963

3. Cellular metabolism in genetic transformation of pneumococci: requirement for protein synthesis during induction of competence.

Authors: A Tomasz
Journal: J Bacteriol Date: 1970-03 Impact factor: 3.490

9. Incorporation of thymidine and amino acids into deoxyribonucleic acid and acid-insoluble cell structures in pneumococcal cultures synchronized for competence to transform.

Authors: H Ephrussi-Taylor; B A Freed
Journal: J Bacteriol Date: 1964-05 Impact factor: 3.490

Effect of D-cycloserine on transformation in group H streptococcus, strain Challis.

1. BIOCHEMICAL ASPECTS OF COMPETENCE IN THE BACILLUS SUBTILIS TRANSFORMATION SYSTEM. I. CHEMICAL COMPOSITION OF CELL WALLS.

2. THE EFFECT OF ENVIRONMENTAL FACTORS ON TRANSFORMABILITY OF A STREPTOCOCCUS.

3. Cellular metabolism in genetic transformation of pneumococci: requirement for protein synthesis during induction of competence.

4. Effect of selected antibiotics and other inhibitors on competence development in Haemophilus influenzae.

5. Transformation in quasi spheroplasts of Bacillus subtilis.

6. Binding of deoxyribonucleic acid by cell walls of transformable and nontransformable streptococci.

7. Transformability of streptomycin-resistant group H streptococci.

8. Periodate inhibition of transformation and competence development in Haemophilus influenzae.

9. Incorporation of thymidine and amino acids into deoxyribonucleic acid and acid-insoluble cell structures in pneumococcal cultures synchronized for competence to transform.

10. BIOSYNTHETIC LATENCY IN EARLY STAGES OF DEOXYRIBONUCLEIC ACIDTRANSFORMATION IN BACILLUS SUBTILIS.

1. Relationship of macromolecular synthesis to competence induction in a group H streptococcus.

2. Inhibition of Neisseria catarrhalis NE-11 transformation.

3. Effect of competence induction on macromolecular synthesis in a group H streptococcus.