Literature DB >> 499424

Possible mutagenic activity of saccharin.

H W Renner.   

Abstract

A mutagenic effect of saccharin in Chinese hamsters, using the in vivo SCE test, was observed when massive overdoses were administered; cyclamate was not mutagenic.

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Year:  1979        PMID： 499424     DOI： 10.1007/bf01964011

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

Review 1.  The mutagenicity of saccharin.

Authors:  P G Kramers
Journal:  Mutat Res       Date:  1975       Impact factor: 2.433

2.  Analysis of sister chromatid exchange formation in vivo in mouse spermatogonia as a new test system for environmental mutagens.

Authors:  J W Allen; S A Latt
Journal:  Nature       Date:  1976-04-01       Impact factor: 49.962

3.  Differential chromatid staining by in vivo treatment as a mutagenicity test system.

Authors:  W Vogel; T Bauknecht
Journal:  Nature       Date:  1976-04-01       Impact factor: 49.962

4.  A simplified technique for in vivo analysis of sister-chromatid exchanges using 5-bromodeoxyuridine tablets.

Authors:  J W Allen; C F Shuler; R W Mendes; S A Latt
Journal:  Cytogenet Cell Genet       Date:  1977

5.  Chemical mutagenesis. The Chinese hamster bone marrow as an in vivo test system. II. Correlation with in vitro results on Chinese hamster fibroblasts and human fibroblasts and lymphocytes.

Authors:  D T Arakaki; W Schmid
Journal:  Humangenetik       Date:  1971

6.  Saccharin-induced sister chromatid exchanges in Chinese hamster and human cells.

Authors:  S Wolff; B Rodin
Journal:  Science       Date:  1978-05-05       Impact factor: 47.728
  6 in total

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