Evaluation of Thyopac-3 test in the in-vitro assessment of thyroid function.

Thyopac-3, a new commercial test kit for the in-vitro assessment of thyroid function, has been appraised in a group of 411 patients. The Thyopac-3 test was found to be simple and rapid to perform and accurate in diagnosis. Of 117 patients shown to be euthyroid by other criteria, 5% had Thyopac-3 values outside the normal range (derived from a group of 135 normal patients), and 10 of 79 thyrotoxic and 4 of 37 hypothyroid patients had values within the normal range.In a direct comparison in 190 patients with the resin uptake test the Thyopac-3 test emerged very favourably in regard to diagnostic accuracy and was technically easier and quicker to carry out. There was a non-linear negative correlation between results from the two procedures.