Literature DB >> 498080

Pyrazofurin metabolism, enzyme inhibition, and resistance in L5178Y cells.

D E Dix, C P Lehman, A Jakubowski, J D Moyer, R E Handschumacher.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 498080

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


× No keyword cloud information.
  7 in total

1.  Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase.

Authors:  Maria Elena Meza-Avina; Lianhu Wei; Yan Liu; Ewa Poduch; Angelica M Bello; Ram K Mishra; Emil F Pai; Lakshmi P Kotra
Journal:  Bioorg Med Chem       Date:  2010-04-09       Impact factor: 3.641

2.  Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.

Authors:  Jan Balzarini; Federico Gago; Wim Kulik; André B P van Kuilenburg; Anna Karlsson; Matt A Peterson; Morris J Robins
Journal:  J Biol Chem       Date:  2012-06-24       Impact factor: 5.157

Review 3.  Purine and pyrimidine pathways as targets in Plasmodium falciparum.

Authors:  María Belén Cassera; Yong Zhang; Keith Z Hazleton; Vern L Schramm
Journal:  Curr Top Med Chem       Date:  2011       Impact factor: 3.295

4.  Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

Authors:  David B Sykes; Youmna S Kfoury; François E Mercier; Mathias J Wawer; Jason M Law; Mark K Haynes; Timothy A Lewis; Amir Schajnovitz; Esha Jain; Dongjun Lee; Hanna Meyer; Kerry A Pierce; Nicola J Tolliday; Anna Waller; Steven J Ferrara; Ashley L Eheim; Detlef Stoeckigt; Katrina L Maxcy; Julien M Cobert; Jacqueline Bachand; Brian A Szekely; Siddhartha Mukherjee; Larry A Sklar; Joanne D Kotz; Clary B Clish; Ruslan I Sadreyev; Paul A Clemons; Andreas Janzer; Stuart L Schreiber; David T Scadden
Journal:  Cell       Date:  2016-09-15       Impact factor: 41.582

5.  In vitro susceptibilities of Plasmodium falciparum to compounds which inhibit nucleotide metabolism.

Authors:  S A Queen; D L Jagt; P Reyes
Journal:  Antimicrob Agents Chemother       Date:  1990-07       Impact factor: 5.191

6.  Identification of the C-Glycoside Synthases during Biosynthesis of the Pyrazole-C-Nucleosides Formycin and Pyrazofurin.

Authors:  Daan Ren; Shao-An Wang; Yeonjin Ko; Yujie Geng; Yasushi Ogasawara; Hung-Wen Liu
Journal:  Angew Chem Int Ed Engl       Date:  2019-10-07       Impact factor: 15.336

Review 7.  Re-Discovery of Pyrimidine Salvage as Target in Cancer Therapy.

Authors:  Melanie Walter; Patrick Herr
Journal:  Cells       Date:  2022-02-20       Impact factor: 6.600
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.