Literature DB >> 496910

Enhanced stability of the Na+-dependent amino acid-transport system after lymphocyte activation.

A F Borghetti, J E Kay.   

Abstract

The Na+-dependent transport system for the amino acid proline in unstimulated lymphocytes decays with a half-life of about 4 h when protein synthesis is inhibited by cycloheximide, but the system in mitogen-activated lymphocytes is more stable. However, the early increase in activity of this transport system after mitogen addition is not due to a direct effect on its stability, but is a secondary effect requiring protein synthesis.

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Year:  1979        PMID： 496910      PMCID： PMC1161254          DOI： 10.1042/bj1820237

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

1.  The control of protein synthesis during the stimulation of lymphocytes by phytohaemagglutinin. III. Poly(U) translation and the rate of polypeptide chain elongation.

Authors:  J E Kay; T Ahern; V J Lindsay; J Sampson
Journal:  Biochim Biophys Acta       Date:  1975-01-20

2.  Puromycin effect on amino acid transport: differential rates of carrier protein turnover.

Authors:  J M Phang; D L Valle; L Fisher; A Granger
Journal:  Am J Physiol       Date:  1975-01

3.  Effect of actinomycin on protein synthesis by lymphocytes.

Authors:  J E Kay
Journal:  Nature       Date:  1967-07-01       Impact factor: 49.962

4.  Regulation of amino acid transport in chick embryo heart cells. II. Adaptive control sites for the "A mediation".

Authors:  R Franchi-Gazzola; G C Gazzola; P Ronchi; V Saibene; G G Guidotti
Journal:  Biochim Biophys Acta       Date:  1973-01-26

5.  Increased transport of 2-aminoisobutyric acid in rat lymphocytes stimulated with concanavalin A.

Authors:  K J van den Berg; I Betel
Journal:  Exp Cell Res       Date:  1973-01       Impact factor: 3.905

6.  Enhanced transport of natural amino acids after activation of pig lymphocytes.

Authors:  A F Borghetti; J E Kay; K P Wheeler
Journal:  Biochem J       Date:  1979-07-15       Impact factor: 3.857

7.  Serum-mediated regulation of amino acid transport in cultured chick embryo fibroblasts.

Authors:  M Tramacere; A F Borghetti; G G Guidotti
Journal:  J Cell Physiol       Date:  1977-12       Impact factor: 6.384

8.  Amino acid transport by aggregates of cultured chicken heart cells. Effect of insulin.

Authors:  L J Elsas; F B Wheeler; D J Danner; R L DeHaan
Journal:  J Biol Chem       Date:  1975-12-25       Impact factor: 5.157

9.  Induction of amino acid transport in primary cultures of adult rat liver parenchymal cells by insulin.

Authors:  R F Kletzien; M W Pariza; J E Becker; V R Potter; F R Butcher
Journal:  J Biol Chem       Date:  1976-05-25       Impact factor: 5.157

10.  The rapid induction by phytohemagglutinin of increased alpha-aminoisobutyric acid uptake by lymphocytes.

Authors:  J Mendelsohn; A Skinner; S Kornfeld
Journal:  J Clin Invest       Date:  1971-04       Impact factor: 14.808
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  2 in total

1.  Effect of cyclosporin A on lymphocyte activation by the calcium ionophore A23187.

Authors:  J E Kay; C R Benzie; A F Borghetti
Journal:  Immunology       Date:  1983-11       Impact factor: 7.397

2.  System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis.

Authors:  Bruno Raposo; Daniëlle Vaartjes; Emma Ahlqvist; Kutty-Selva Nandakumar; Rikard Holmdahl
Journal:  Immunology       Date:  2015-10-05       Impact factor: 7.397
  2 in total

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