Literature DB >> 496896

Crystallization of the Fv fragment of mouse myeloma protein M315.

R Aschaffenburg, D C Phillips, D R Rose, B J Sutton, S K Dower, R A Dwek.   

Abstract

The Fv fragment of mouse myeloma protein M313 was crystallized from poly(ethylene glycol) solution in the form of monoclinic crystals, space group C2 and unit cell dimensions a = 5.96 nm (59.6 A), b = 5.66 nm (56.6 A), c = 13.79 nm (13.9 A) and beta = 99.7 degrees. Some unusual effects of poly(ethylene glycol)on protein crystals were noted and are discussed.

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Year:  1979        PMID： 496896      PMCID： PMC1161181          DOI： 10.1042/bj1810497

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  16 in total

1.  Structure of an antibody combining site by magnetic resonance.

Authors:  R A Dwek; S Wain-Hobson; S Dower; P Gettins; B Sutton; S J Perkins; D Givol
Journal:  Nature       Date:  1977-03-03       Impact factor: 49.962

2.  The gross architecture of an antibody-combining site as determined by spin-label mapping.

Authors:  B J Sutton; P Gettins; D Givol; D Marsh; S Wain-Hobson; K J Willan; R A Dwek
Journal:  Biochem J       Date:  1977-08-01       Impact factor: 3.857

Review 3.  Correlations between three-dimensional structure and function of immunoglobulins.

Authors:  R J Poljak
Journal:  CRC Crit Rev Biochem       Date:  1978

4.  Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.

Authors:  E A Padlan; D R Davies; I Pecht; D Givol; C Wright
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1977

Review 5.  The structural basis of antibody complementarity.

Authors:  E A Kabat
Journal:  Adv Protein Chem       Date:  1978

6.  Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain.

Authors:  S Tonegawa; A M Maxam; R Tizard; O Bernard; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

7.  Mouse myeloma proteins with antihapten antibody acitivity. The protein produced by plasma cell tumor MOPC-315.

Authors:  H N Eisen; E S Simms; M Potter
Journal:  Biochemistry       Date:  1968-11       Impact factor: 3.162

8.  Solvent content of protein crystals.

Authors:  B W Matthews
Journal:  J Mol Biol       Date:  1968-04-28       Impact factor: 5.469

9.  Crystallization of proteins from polyethylene glycol.

Authors:  A McPherson
Journal:  J Biol Chem       Date:  1976-10-25       Impact factor: 5.157

10.  Resonance Raman-spectroscopic studies of the hapten features involved in the binding of 2,4-dinitrophenyl haptens by the mouse myeloma proteins MOPC 315 and MOPC 460.

Authors:  K Kumar; D J Phelps; P R Carey; N M Young
Journal:  Biochem J       Date:  1978-11-01       Impact factor: 3.857
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