Literature DB >> 4963772

Studies with hydroxyurea. VII. Hydroxyurea and the synthesis of functional proteins.

H S Rosenkranz, E B Winshell, A Mednis, H S Carr, C J Ellner.   

Abstract

Hydroxyurea affected neither the synthesis nor the degradation of bacterial messenger-ribonucleic acid. The proteins made by hydroxyurea-treated cells were structurally intact and fully functional. Since the expression of the lethal action of hydroxyurea requires active protein production, the data indicate that treated cells do not die as the result of the synthesis of abnormal proteins.

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Year:  1967        PMID： 4963772      PMCID： PMC276771          DOI： 10.1128/jb.94.4.1025-1033.1967

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  43 in total

1.  HOMOLOGY BETWEEN RNA FROM ROUS SARCOMA VIROUS AND DNA FROM ROUS SARCOMA VIRUS-INFECTED CELLS.

Authors:  H M TEMIN
Journal:  Proc Natl Acad Sci U S A       Date:  1964-08       Impact factor: 11.205

2.  PRELIMINARY SURVEY OF HYDROXYUREA (NSC-32065) AS A TERATOGEN.

Authors:  M L MURPHY; S CHAUBE
Journal:  Cancer Chemother Rep       Date:  1964-08

3.  Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA.

Authors:  S P CHAMPE; S BENZER
Journal:  Proc Natl Acad Sci U S A       Date:  1962-04-15       Impact factor: 11.205

4.  Mutants of Escherichia coli constitutive for alkaline phosphatase.

Authors:  A TORRIANI; F ROTHMAN
Journal:  J Bacteriol       Date:  1961-05       Impact factor: 3.490

5.  A hypothesis on a possible competitive relation between DNA synthesis and protein synthesis.

Authors:  S S COHEN
Journal:  Cancer Res       Date:  1960-06       Impact factor: 12.701

6.  Mutants of Escherichia coli requiring methionine or vitamin B12.

Authors:  B D DAVIS; E S MINGIOLI
Journal:  J Bacteriol       Date:  1950-07       Impact factor: 3.490

7.  The effect of hydroxyurea on virus development. II. Vaccinia virus.

Authors:  H S Rosenkranz; H M Rose; C Morgan; K C Hsu
Journal:  Virology       Date:  1966-04       Impact factor: 3.616

8.  Hydroxyurea: inhibition of deoxyribonucleic acid synthesis in regenerating liver of rats.

Authors:  H S Schwartz; M Garofalo; S S Sternberg; F S Philips
Journal:  Cancer Res       Date:  1965-12       Impact factor: 12.701

9.  Effect of hydroxyurea on virus development. I. Electron microscopic study of the effect on the development of bacteriophage T4.

Authors:  W Margaretten; C Morgan; H S Rosenkranz; H M Rose
Journal:  J Bacteriol       Date:  1966-02       Impact factor: 3.490

10.  HYDROXYUREA: INHIBITORY EFFECT ON DNA METABOLISM.

Authors:  C W YOUNG; S HODAS
Journal:  Science       Date:  1964-11-27       Impact factor: 47.728
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  10 in total

1.  Effects of antimetabolites on the production of tubular structures in Vero cells infected with herpes simplex virus type 2.

Authors:  H Oda; R Mori; J Miyazono; T Iwasaka
Journal:  Arch Virol       Date:  1979       Impact factor: 2.574

2.  Electron microscopy of herpes simplex virus. 3. Effect of hydroxyurea.

Authors:  S Nii; H S Rosenkranz; C Morgan; H M Rose
Journal:  J Virol       Date:  1968-10       Impact factor: 5.103

3.  Action of hydroxyurea on Anabaena variabilis. II. Effects of pre- and post-treatment with chloramphenicol and base analogues.

Authors:  M K Singh; H D Kumar
Journal:  Arch Mikrobiol       Date:  1969

4.  Genome-wide screening with hydroxyurea reveals a link between nonessential ribosomal proteins and reactive oxygen species production.

Authors:  Toru Nakayashiki; Hirotada Mori
Journal:  J Bacteriol       Date:  2013-01-04       Impact factor: 3.490

5.  Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.

Authors:  Bryan W Davies; Michael A Kohanski; Lyle A Simmons; Jonathan A Winkler; James J Collins; Graham C Walker
Journal:  Mol Cell       Date:  2009-12-11       Impact factor: 17.970

6.  The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics.

Authors:  Tara F Mahoney; Thomas J Silhavy
Journal:  J Bacteriol       Date:  2013-01-18       Impact factor: 3.490

7.  Reversible inhibition of herpes simplex virus replication by hydroxyurea.

Authors:  H S Rosenkranz; Y Becker
Journal:  Antimicrob Agents Chemother       Date:  1973-03       Impact factor: 5.191

8.  Dynamic assembly of Hda and the sliding clamp in the regulation of replication licensing.

Authors:  Jin S Kim; Michael T Nanfara; Sundari Chodavarapu; Kyeong S Jin; Vignesh M P Babu; Mohamed A Ghazy; Scisung Chung; Jon M Kaguni; Mark D Sutton; Yunje Cho
Journal:  Nucleic Acids Res       Date:  2017-04-20       Impact factor: 16.971

9.  Hydroxyurea Induces a Stress Response That Alters DNA Replication and Nucleotide Metabolism in Bacillus subtilis.

Authors:  Katherine J Wozniak; Lyle A Simmons
Journal:  J Bacteriol       Date:  2021-07-08       Impact factor: 3.490

10.  Biochemical Characterization of the Split Class II Ribonucleotide Reductase from Pseudomonas aeruginosa.

Authors:  Mikael Crona; Anders Hofer; Juan Astorga-Wells; Britt-Marie Sjöberg; Fredrik Tholander
Journal:  PLoS One       Date:  2015-07-30       Impact factor: 3.240
  10 in total

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