Literature DB >> 4956

Long-term hypotensive effect of atenolol (ICI 66.082), a new beta-adrenergic blocking agent.

L Hansson, B E Karlberg, H Aberg, A Westerlund, S Jameson, N C Henningsen.   

Abstract

A report is given from an on-going multicenter trial in Sweden, in which 117 hypertensive patients have been treated with a new cardioselective beta-adrenergic blocking agent, atenolol (ICI 66.082, Tenormin) for an average of six months (range 2-21). Statistically significant reductions of BP were observed, recumbent by 29/19 mmHg (p less than 0.0001) and standing by 28/18 mmHg (p less than 0.0001). Few and comparatively mild side-effects were seen.

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Year:  1976        PMID: 4956     DOI: 10.1111/j.0954-6820.1976.tb06729.x

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN: 0001-6101


  4 in total

1.  Dose-response in hypertension in general practice.

Authors:  S R Mayhew
Journal:  Proc R Soc Med       Date:  1977

2.  Central nervous system side-effects with hydrophilic and lipophilic beta-blockers.

Authors:  A Westerlund
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953

Review 3.  Atenolol: a review of its pharmacological properties and therapeutic efficacy in angina pectoris and hypertension.

Authors:  R C Heel; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1979-06       Impact factor: 9.546

4.  A comparison of the antihypertensive effect of atenolol (ICI 66 082) and propranolol.

Authors:  L Hansson; A Westerlund; H Aberg; B E Karlberg
Journal:  Eur J Clin Pharmacol       Date:  1976-03-22       Impact factor: 2.953

  4 in total

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