Literature DB >> 786662

A comparison of the antihypertensive effect of atenolol (ICI 66 082) and propranolol.

L Hansson, A Westerlund, H Aberg, B E Karlberg.   

Abstract

Propranolol was given to 30 patients with essential hypertension following randomised, double-blind administration of either placebo or a new cardioselective beta-adrenergic receptor antagonist, atenolol (Tenormin, ICI 66 082). Both atenolol and propranolol caused statistically significant reduction of recumbent and erect blood pressure and heart rate. There were no important differences between these variables on comparison of atenolol and propranolol.

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Year:  1976        PMID： 786662     DOI： 10.1007/bf00606549

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  17 in total

1.  NETHALIDE, A BETA ADRENERGIC BLOCKING AGENT.

Authors:  G SCHROEDER; L WERKOE
Journal:  Clin Pharmacol Ther       Date:  1964 Mar-Apr       Impact factor: 6.875

2.  Propranolol therapy in essential hypertension.

Authors:  H Lydtin; T Kusus; W Daniel; W Schierl; M Ackenheil; H Kempter; G Lohmöller; M Niklas; I Walter
Journal:  Am Heart J       Date:  1972-05       Impact factor: 4.749

3.  Assessment of -adrenergic blocking and non-specific properties of propranolol.

Authors:  D J Coltart
Journal:  Br Heart J       Date:  1971-07

4.  Studies on the antihypertensive action of the optical isomers of propranolol in man.

Authors:  K H Rahn; A Hawlina; F Kersting; G Planz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

5.  Propranolol in hypertension: a study of long-term therapy, 1964-1970.

Authors:  F J Zacharias; K J Cowen; J Prestt; J Vickers; B G Wall
Journal:  Am Heart J       Date:  1972-06       Impact factor: 4.749

6.  The paradox of beta-adrenergic blockade in hypertension.

Authors:  E D Frohlich; R C Tarazi; H P Dustan; I H Page
Journal:  Circulation       Date:  1968-03       Impact factor: 29.690

7.  Initial clinical experience with I.C.I. 66.082, a new beta-adrenergic blocking agent, in hypertension.

Authors:  L Hansson; H Aberg; S Jameson; B Karlberg; R Malmcrona
Journal:  Acta Med Scand       Date:  1973-12

8.  A new type of cardioselective adrenoceptive blocking drug.

Authors:  A M Barrett; J Carter; J D Fitzgerald; R Hull; D Le Count
Journal:  Br J Pharmacol       Date:  1973-06       Impact factor: 8.739

9.  Hypotensive action of ICI66.082, a new beta-adrenergic blocking agent.

Authors:  L Hansson; N C Henningsen; B Karlberg; H Aberg; S Jameson; R Malmcrona; C Hersvall
Journal:  Int J Clin Pharmacol       Date:  1974-10

10.  Treatment of hypertension with propranolol.

Authors:  B N Prichard; P M Gillam
Journal:  Br Med J       Date:  1969-01-04
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  8 in total

Review 1.  Hypertension: which beta-blocker?

Authors:  H J Waal-Manning
Journal:  Drugs       Date:  1976-12       Impact factor: 9.546

2.  Randomised trial comparing propranolol with atenolol in immediate treatment of suspected myocardial infarction.

Authors:  R G Wilcox; J M Roland; D C Banks; J R Hampton; J R Mitchell
Journal:  Br Med J       Date:  1980-03-29

Review 3.  Atenolol: a review of its pharmacological properties and therapeutic efficacy in angina pectoris and hypertension.

Authors:  R C Heel; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1979-06       Impact factor: 9.546

4.  Prevention and reversal of isolation-induced systolic arterial hypertension in rats by treatment with beta-adrenoceptor antagonists.

Authors:  T Bennett; S M Gardiner
Journal:  Br J Pharmacol       Date:  1979-02       Impact factor: 8.739

5.  Transplacental passage of atenolol in man.

Authors:  A Melander; B Niklasson; I Ingemarsson; H Liedholm; B Scherstén; N O Sjöberg
Journal:  Eur J Clin Pharmacol       Date:  1978-11-16       Impact factor: 2.953

6.  Antihypertensive effect of a non-selective (propranolol) and a cardioselective (metoprolol) beta-adrenoceptor blocking agent at rest and during exercise.

Authors:  N Clausen; T Damsgaard; K Mellemgaard
Journal:  Br J Clin Pharmacol       Date:  1979-04       Impact factor: 4.335

7.  Comparative study of metoprolol and alpha-methyldopa in untreated essential hypertension.

Authors:  R H Bergstrand; J A Vedin; C E Wilhelmsson; G Berglund
Journal:  Eur J Clin Pharmacol       Date:  1976       Impact factor: 2.953

8.  Cardiovascular reflexes in patients after myocardial infarction. Effect of long-term treatment with beta-adrenoceptor antagonists.

Authors:  T Bennett; R G Wilcox; J R Hampton
Journal:  Br Heart J       Date:  1980-09
  8 in total

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