Literature DB >> 4952520

The antitumor activity of Cu(II)KTS, the copper (II) chelate of 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazone).

J A Crim, H G Petering.   

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Year:  1967        PMID: 4952520

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


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  9 in total

1.  A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo.

Authors:  Chad N Hancock; Luke H Stockwin; Bingnan Han; Raymond D Divelbiss; Jung Ho Jun; Sanjay V Malhotra; Melinda G Hollingshead; Dianne L Newton
Journal:  Free Radic Biol Med       Date:  2010-11-04       Impact factor: 7.376

2.  Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells.

Authors:  Kenichi Shimada; Eduard Reznik; Michael E Stokes; Lakshmi Krishnamoorthy; Pieter H Bos; Yuyu Song; Christine E Quartararo; Nen C Pagano; Darren R Carpizo; Ana C deCarvalho; Donald C Lo; Brent R Stockwell
Journal:  Cell Chem Biol       Date:  2018-03-22       Impact factor: 8.116

3.  Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines.

Authors:  Alessandro Zanella; Valentina Gandin; Marina Porchia; Fiorenzo Refosco; Francesco Tisato; Francesca Sorrentino; Guido Scutari; Maria Pia Rigobello; Cristina Marzano
Journal:  Invest New Drugs       Date:  2010-06-22       Impact factor: 3.850

4.  Anti-Prostate Cancer Activity of 8-Hydroxyquinoline-2-Carboxaldehyde-Thiosemicarbazide Copper Complexes by Fluorescent Microscopic Imaging.

Authors:  Fang Xie; Fangyu Peng
Journal:  J Fluoresc       Date:  2017-06-26       Impact factor: 2.217

5.  An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII.

Authors:  Paul S Donnelly; Jeffrey R Liddell; SinChun Lim; Brett M Paterson; Michael A Cater; Maria S Savva; Alexandra I Mot; Janine L James; Ian A Trounce; Anthony R White; Peter J Crouch
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-15       Impact factor: 11.205

6.  Metal binding drugs induce synthesis of four proteins in normal cells.

Authors:  W Levinson; J Idriss; J Jackson
Journal:  Biol Trace Elem Res       Date:  1979-03       Impact factor: 3.738

7.  Mechanistic characterization of a copper containing thiosemicarbazone with potent antitumor activity.

Authors:  Henning Karlsson; Mårten Fryknäs; Sara Strese; Joachim Gullbo; Gunnar Westman; Ulf Bremberg; Tobias Sjöblom; Tatjana Pandzic; Rolf Larsson; Peter Nygren
Journal:  Oncotarget       Date:  2017-05-02

8.  Synthesis and electrophilic substitutions of novel pyrazolo[1,5-c]-1,2,4-triazolo[4,3-a]pyrimidines.

Authors:  Kamal F M Atta
Journal:  Molecules       Date:  2011-08-18       Impact factor: 4.411

9.  Synthesis, cytotoxic activity, and DNA binding properties of copper (II) complexes with hesperetin, naringenin, and apigenin.

Authors:  Mingxiong Tan; Jinchan Zhu; Yingming Pan; Zhenfeng Chen; Hong Liang; Huagang Liu; Hengshan Wang
Journal:  Bioinorg Chem Appl       Date:  2009-10-08       Impact factor: 7.778

  9 in total

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