Literature DB >> 4950816

Mechanism of action of negamycin in Escherichia coli K12. II. Miscoding activity in polypeptide synthesis directed by snythetic polynucleotide.

S Mizuno, K Nitta, H Umezawa.   

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Year:  1970        PMID: 4950816

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


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  5 in total

1.  Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.

Authors:  Nelson B Olivier; Roger B Altman; Jonas Noeske; Gregory S Basarab; Erin Code; Andrew D Ferguson; Ning Gao; Jian Huang; Manuel F Juette; Stephania Livchak; Matthew D Miller; D Bryan Prince; Jamie H D Cate; Ed T Buurman; Scott C Blanchard
Journal:  Proc Natl Acad Sci U S A       Date:  2014-11-03       Impact factor: 11.205

2.  Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.

Authors:  Susan J Schroeder; Gregor Blaha; Peter B Moore
Journal:  Antimicrob Agents Chemother       Date:  2007-07-30       Impact factor: 5.191

3.  Ribosomal function and its inhibition by antibiotics in prokaryotes.

Authors:  K H Nierhaus; H G Wittmann
Journal:  Naturwissenschaften       Date:  1980-05

4.  Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens.

Authors:  David C McKinney; Gregory S Basarab; Alexis I Cocozaki; Melinda A Foulk; Matthew D Miller; Anatoly M Ruvinsky; Clay W Scott; Kumar Thakur; Liang Zhao; Ed T Buurman; Sridhar Narayan
Journal:  ACS Med Chem Lett       Date:  2015-07-12       Impact factor: 4.345

5.  Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.

Authors:  Yury S Polikanov; Teresa Szal; Fuyan Jiang; Pulkit Gupta; Ryoichi Matsuda; Masataka Shiozuka; Thomas A Steitz; Nora Vázquez-Laslop; Alexander S Mankin
Journal:  Mol Cell       Date:  2014-10-09       Impact factor: 17.970

  5 in total

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