Literature DB >> 4950815

Mechanism of action of negamycin in Escherichia coli K12. I. Inhibition of initiation of protein synthesis.

S Mizuno, K Nitta, H Umezawa.   

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Year:  1970        PMID: 4950815

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


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  6 in total

1.  Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.

Authors:  Nelson B Olivier; Roger B Altman; Jonas Noeske; Gregory S Basarab; Erin Code; Andrew D Ferguson; Ning Gao; Jian Huang; Manuel F Juette; Stephania Livchak; Matthew D Miller; D Bryan Prince; Jamie H D Cate; Ed T Buurman; Scott C Blanchard
Journal:  Proc Natl Acad Sci U S A       Date:  2014-11-03       Impact factor: 11.205

2.  Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites.

Authors:  Yun Xie; Andrew V Dix; Yitzhak Tor
Journal:  Chem Commun (Camb)       Date:  2010-05-13       Impact factor: 6.222

3.  Structural Insights Lead to a Negamycin Analogue with Improved Antimicrobial Activity against Gram-Negative Pathogens.

Authors:  David C McKinney; Gregory S Basarab; Alexis I Cocozaki; Melinda A Foulk; Matthew D Miller; Anatoly M Ruvinsky; Clay W Scott; Kumar Thakur; Liang Zhao; Ed T Buurman; Sridhar Narayan
Journal:  ACS Med Chem Lett       Date:  2015-07-12       Impact factor: 4.345

Review 4.  Antibiotics and compounds affecting tanslation by eukaryotic ribosomes. Specific enhancement of aminoacyl-tRNA binding by methylaxnthines.

Authors:  L Carrasco; C Fernandez-Puentes; D Vazquez
Journal:  Mol Cell Biochem       Date:  1976-02-16       Impact factor: 3.396

5.  Markerless Escherichia coli rrn Deletion Strains for Genetic Determination of Ribosomal Binding Sites.

Authors:  Selwyn Quan; Ole Skovgaard; Robert E McLaughlin; Ed T Buurman; Catherine L Squires
Journal:  G3 (Bethesda)       Date:  2015-10-04       Impact factor: 3.154

6.  Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.

Authors:  Yury S Polikanov; Teresa Szal; Fuyan Jiang; Pulkit Gupta; Ryoichi Matsuda; Masataka Shiozuka; Thomas A Steitz; Nora Vázquez-Laslop; Alexander S Mankin
Journal:  Mol Cell       Date:  2014-10-09       Impact factor: 17.970

  6 in total

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