Literature DB >> 4944401

Selection of ribosomal mutants by antibiotic suppression in yeast.

F T Bayliss, R T Vinopal.   

Abstract

Wild-type Saccharomyces cerevisiae is highly resistant to streptomycin. A histidine auxotroph was found which could grow without histidine in the presence of high concentrations of streptomycin. Selection for derivatives of this strain which could be suppressed by much lower concentrations of streptomycin yielded streptomycin-sensitive mutants which are cold-sensitive and have altered ribosomal profiles.

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Year:  1971        PMID： 4944401     DOI： 10.1126/science.174.4016.1339

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  19 in total

1.  The effect of paromomycin and [psi] on the suppression of mitochondrial mutations in Saccharomyces cerevisiae.

Authors:  G Dujardin; P Lund; P P Slonimski
Journal:  Curr Genet       Date:  1984-12       Impact factor: 3.886

2.  Genetic evidence of ribosomal antisuppressors in Podospora anserina.

Authors:  M Picard-Bennoun
Journal:  Mol Gen Genet       Date:  1976-09-23

3.  Cold-sensitive mutants in Aspergillus nidulans. I. Isolation and general characterisation.

Authors:  C Waldron; C F Roberts
Journal:  Mol Gen Genet       Date:  1974

4.  Cold-sensitive mutants in Aspergillus nidulans. II. Mutations affecting ribosome production.

Authors:  C Waldron; C F Roberts
Journal:  Mol Gen Genet       Date:  1974

5.  Temperature-dependent expression of transformation by cold-sensitive mutant of murine sarcoma virus.

Authors:  K Somers; S Kit
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

6.  Incompatibility in the fungus Podospora anserina. Are the mutations abolishing the incompatibility reaction ribosomal mutations?

Authors:  J Bernet; J Bégueret; J Labarére
Journal:  Mol Gen Genet       Date:  1973-07-31

7.  Cold-sensitive mutants of Neurospora crassa.

Authors:  D R Roberds; A G DeBusk
Journal:  J Bacteriol       Date:  1973-09       Impact factor: 3.490

8.  Neurospora crassa cytoplasmic ribosomes: isolation and characterization of a cold-sensitive mutant defective in ribosome biosynthesis.

Authors:  S C Schlitt; P J Russell
Journal:  J Bacteriol       Date:  1974-11       Impact factor: 3.490

9.  Cold-sensitive mutants of Drosophila melanogaster defective in ribosome assembly.

Authors:  E V Falke; T R Wright
Journal:  Genetics       Date:  1975-12       Impact factor: 4.562

10.  Mutation in Saccharomyces cerevisiae conferring streptomycin and cold sensitivity by affecting ribosome formation and function.

Authors:  F T Bayliss; J L Ingrahm
Journal:  J Bacteriol       Date:  1974-05       Impact factor: 3.490
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