Literature DB >> 4942910

Specific heterologous enhancement of immune responses.

A S Rubin, A H Coons.   

Abstract

In suspension cultures of mouse spleen cells, the addition of small amounts (1-100 ng) of a heterologous antigen to which the donor mice had been primed significantly increased the number of anti-sheep erythrocyte plaques appearing after stimulation with sheep erythrocytes. A similar addition to identical cultures from unprimed donors produced a small depression in the number of such plaques.

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Year:  1971        PMID: 4942910      PMCID: PMC389266          DOI: 10.1073/pnas.68.8.1665

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  19 in total

1.  The immunologic behavior of baby pigs. II. Production of antibodies in newborn pigs.

Authors:  D SEGRE; M L KAEBERLE
Journal:  J Immunol       Date:  1962-12       Impact factor: 5.422

2.  The influence of colostrum on antibody response in baby pigs.

Authors:  A B HOERLEIN
Journal:  J Immunol       Date:  1957-02       Impact factor: 5.422

3.  Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells.

Authors:  A B STAVITSKY
Journal:  J Immunol       Date:  1954-05       Impact factor: 5.422

4.  Is delayed sensitivity a preparation for antibody synthesis?

Authors:  S Leskowitz
Journal:  J Immunol       Date:  1968-09       Impact factor: 5.422

5.  Ontogeny of the immune response. I. Development of immunoglobulins in germfree and conventional colostrum-deprived piglets.

Authors:  Y B Kim; S G Bradley; D W Watson
Journal:  J Immunol       Date:  1966-07       Impact factor: 5.422

6.  The antibody response: a model based on antagonistic actions of antigen.

Authors:  D W Talmage; D S Pearlman
Journal:  J Theor Biol       Date:  1963-09       Impact factor: 2.691

7.  Cell interactions in the primary immune response in vitro: a requirement for specific cell clusters.

Authors:  D E Mosier
Journal:  J Exp Med       Date:  1969-02-01       Impact factor: 14.307

8.  Enhancement of antibody formation by whole body x-radiation.

Authors:  F J DIXON; P J McCONAHEY
Journal:  J Exp Med       Date:  1963-05-01       Impact factor: 14.307

9.  The requirement of more than one antigenic determinant for immunogenicity.

Authors:  K Rajewsky; V Schirrmacher; S Nase; N K Jerne
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307

10.  Enhancement of antibody synthesis by 6-mercaptopurine.

Authors:  D Chanmougan; R S Schwartz
Journal:  J Exp Med       Date:  1966-09-01       Impact factor: 14.307

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  14 in total

1.  Correlations between immunoglobulin- and antibody-synthesizing cells during primary and secondary immune responses of rats immunized with peroxidase.

Authors:  J C Antoine; S Avrameas
Journal:  Immunology       Date:  1976-04       Impact factor: 7.397

2.  Antagonistic interactions between enhancing and suppressor factors that regulate the humoral immune response.

Authors:  A S Rubin
Journal:  Immunology       Date:  1979-04       Impact factor: 7.397

3.  Non-specific suppression of the initiation of the immune response to a heterologous immunogen by supernatants from specifically stimulated, primed lymphoid cells.

Authors:  G N Douglas; A S Rubin
Journal:  Immunology       Date:  1977-05       Impact factor: 7.397

4.  In vitro studies of 'antigenic competition'. II. Reconstitution of the immune defect and the relationship between antigen-induced suppression and non-specific enhancement.

Authors:  H Pross; D Eidinger
Journal:  Immunology       Date:  1973-08       Impact factor: 7.397

5.  Partial characterization of an immunoenhancing factor from allogeneic human lymphocyte cell lines.

Authors:  A S Rubin; A B Macdonald
Journal:  Immunology       Date:  1976-01       Impact factor: 7.397

6.  Escape from antibody-mediated immune suppression in vitro by delayed-type hypersensitivity reaction.

Authors:  C C Muscoplat; T M Setcavage; Y B Kim
Journal:  Infect Immun       Date:  1977-02       Impact factor: 3.441

7.  Isolation and partial characterization of an antibody enhancing factor from leukaemic owl monkey cell cultures.

Authors:  A B MacDonald; C E Fraser; A S Rubin
Journal:  Immunology       Date:  1978-01       Impact factor: 7.397

8.  Specific heterologous enhancement of immune responses. II. Immunological memory cells of thymic origin.

Authors:  A S Rubin; A H Coons
Journal:  J Exp Med       Date:  1972-02-01       Impact factor: 14.307

9.  Specific heterologous enhancement of immune responses. IV. Specific generation of a thymus-derived enhancing factor.

Authors:  A S Rubin; A H Coons
Journal:  J Exp Med       Date:  1972-12-01       Impact factor: 14.307

10.  Bystander help in primary immune responses in vivo.

Authors:  P E Jensen; J A Kapp
Journal:  J Exp Med       Date:  1986-09-01       Impact factor: 14.307

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