| Literature DB >> 342395 |
A B MacDonald, C E Fraser, A S Rubin.
Abstract
Herpesvirus saimiri inoculated into owl monkeys (Aotus trivirgatus) causes leukaemia and lymphoma. Peripheral lymphocytes from leukaemic monkeys grown in culture are predominantly T lymphocytes. The supernatants from these cultures contain a factor which enhances the antibody response of murine B cells to sheep red blood cells (SRBC). The factor has been partially characterized by ammonium sulphate precipitation, DEAE-chromatography, gel filtration over Sephadex G-150 and disc-gel electrophoresis. The enhancing factor is a protein with a molecular weight of approximately 40,000.Entities:
Mesh:
Substances:
Year: 1978 PMID: 342395 PMCID: PMC1457338
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397