Literature DB >> 4942741

Controlled clinical trial of clofazimine in untreated lepromatous leprosy.

A B Karat, A Jeevaratnam, S Karat, P S Rao.   

Abstract

A comparison of clofazimine and dapsone in the management of untreated lepromatous leprosy showed no significant differences between the two drugs in terms of morphological and bacterial indices. The incidence of erythema nodosum leprosum was similar in the two groups. Since dapsone is cheaper than clofazimine it remains the drug of choice for the routine management of untreated lepromatous leprosy.

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Year:  1971        PMID： 4942741      PMCID： PMC1799776          DOI： 10.1136/bmj.4.5786.514

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  7 in total

1.  TREATMENT OF LEPROSY WITH B 663 APPRAISAL OF THE PILOT TRIAL AFTER THREE YEARS.

Authors:  S G BROWNE
Journal:  Lepr Rev       Date:  1965-01       Impact factor: 0.537

2.  "B 663" in the treatment of leprosy. Preliminary report of a pilot trial.

Authors:  S G BROWNE; L M HOGERZEIL
Journal:  Lepr Rev       Date:  1962-01       Impact factor: 0.537

3.  Public Health Weekly Reports for NOVEMBER 26, 1943.

Authors: 
Journal:  Public Health Rep       Date:  1943-11-26       Impact factor: 2.792

4.  Chemotherapeutic trials in leprosy. 3. Pilot trial of a riminophenazine derivative. B.663, in the treatment of lepromatous leprosy.

Authors:  J H Pettit; R J Rees; D S Ridley
Journal:  Int J Lepr Other Mycobact Dis       Date:  1967 Jan-Mar

5.  Leprosy research at the National Institutes of Health: experience with B.663 in the treatment of leprosy.

Authors:  T W Williams; P D Mott; P T Wertlake; J B Rubio; R C Adler; G J Hill; G P Suarez; V Knight
Journal:  Int J Lepr       Date:  1965 Jul-Sep

6.  Double-blind controlled clinical trial of clofazimine in reactive phases of lepromatous leprosy.

Authors:  A B Karat; A Jeevaratnam; S Karat; P S Rao
Journal:  Br Med J       Date:  1970-01-24

7.  MYCOBACTERIUM LEPRAE IN MICE: MINIMAL INFECTIOUS DOSE, RELATIONSHIP BETWEEN STAINING QUALITY AND INFECTIVITY, AND EFFECT OF CORTISONE.

Authors:  C C SHEPARD; D H MCRAE
Journal:  J Bacteriol       Date:  1965-02       Impact factor: 3.490
  7 in total
  4 in total

1.  In vitro activity of clofazimine against rapidly growing nonchromogenic mycobacteria.

Authors:  V Ausina; M J Condom; B Mirelis; M Luquin; P Coll; G Prats
Journal:  Antimicrob Agents Chemother       Date:  1986-05       Impact factor: 5.191

2.  Clofazimine in leprosy.

Authors:  E J Schulz
Journal:  Br Med J       Date:  1972-03-18

3.  Role of superoxide in catalase-peroxidase-mediated isoniazid action against mycobacteria.

Authors:  J Y Wang; R M Burger; K Drlica
Journal:  Antimicrob Agents Chemother       Date:  1998-03       Impact factor: 5.191

4.  miR-323a regulates ERBB4 and is involved in depression.

Authors:  Laura M Fiori; Aron Kos; Rixing Lin; Jean-Francois Théroux; Juan Pablo Lopez; Claudia Kühne; Carola Eggert; Maria Holzapfel; Rosa-Eva Huettl; Naguib Mechawar; Catherine Belzung; El Chérif Ibrahim; Alon Chen; Gustavo Turecki
Journal:  Mol Psychiatry       Date:  2020-11-20       Impact factor: 15.992
  4 in total

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