Literature DB >> 3729356

In vitro activity of clofazimine against rapidly growing nonchromogenic mycobacteria.

V Ausina, M J Condom, B Mirelis, M Luquin, P Coll, G Prats.   

Abstract

The in vitro activity of clofazimine against 80 isolates of rapidly growing nonchromogenic mycobacteria was studied by an agar dilution method. The drug inhibited 96% of strains tested at concentrations less than or equal to 1 microgram/ml, and it appears to be an agent of potential efficacy against Mycobacterium fortuitum and M. chelonae.

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Year:  1986        PMID： 3729356      PMCID： PMC284191          DOI： 10.1128/AAC.29.5.951

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Controlled clinical trial of clofazimine in untreated lepromatous leprosy.

Authors:  A B Karat; A Jeevaratnam; S Karat; P S Rao
Journal:  Br Med J       Date:  1971-11-27

2.  Rapidly growing mycobacteria: testing of susceptibility to 34 antimicrobial agents by broth microdilution.

Authors:  J M Swenson; C Thornsberry; V A Silcox
Journal:  Antimicrob Agents Chemother       Date:  1982-08       Impact factor: 5.191

3.  Enhancement by clofazimine and inhibition by dapsone of production of prostaglandin E2 by human polymorphonuclear leukocytes in vitro.

Authors:  R Anderson
Journal:  Antimicrob Agents Chemother       Date:  1985-02       Impact factor: 5.191

4.  Double-blind controlled clinical trial of clofazimine in reactive phases of lepromatous leprosy.

Authors:  A B Karat; A Jeevaratnam; S Karat; P S Rao
Journal:  Br Med J       Date:  1970-01-24

5.  Antimycobacterial activity of some potential chemotherapeutic compounds.

Authors:  P Damle; J K McClatchy; P R Gangadharam; P T Davidson
Journal:  Tubercle       Date:  1978-06

6.  Identification of clinically significant Mycobacterium fortuitum complex isolates.

Authors:  V A Silcox; R C Good; M M Floyd
Journal:  J Clin Microbiol       Date:  1981-12       Impact factor: 5.948

7.  Activity of some antileprosy compounds against Mycobacterium intracellulare in vitro.

Authors:  P R Gangadharam; E R Candler
Journal:  Am Rev Respir Dis       Date:  1977-04
  7 in total
  2 in total

1.  Therapeutic efficacy of liposomal clofazimine against Mycobacterium avium complex in mice depends on size of initial inoculum and duration of infection.

Authors:  R G Kansal; R Gomez-Flores; I Sinha; R T Mehta
Journal:  Antimicrob Agents Chemother       Date:  1997-01       Impact factor: 5.191

Review 2.  Clofazimine in Nontuberculous Mycobacterial Infections: A Growing Niche.

Authors:  Sarah A McGuffin; Paul S Pottinger; James P Harnisch
Journal:  Open Forum Infect Dis       Date:  2017-07-20       Impact factor: 3.835
  2 in total

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