Literature DB >> 4942325

Studies on the conversion of proinsulin to insulin. I. Conversion in vitro with trypsin and carboxypeptidase B.

W Kemmler, J D Peterson, D F Steiner.   

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Year:  1971        PMID: 4942325

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


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  45 in total

1.  Design and folding of [GluA4(ObetaThrB30)]insulin ("ester insulin"): a minimal proinsulin surrogate that can be chemically converted into human insulin.

Authors:  Youhei Sohma; Qing-Xin Hua; Jonathan Whittaker; Michael A Weiss; Stephen B H Kent
Journal:  Angew Chem Int Ed Engl       Date:  2010-07-26       Impact factor: 15.336

2.  Synthesis of functionally active human proinsulin in a cell-free translation system.

Authors:  A A Kommer; I G Dashkova; R S Esipov; A I Miroshnikov; A S Spirin
Journal:  Dokl Biochem Biophys       Date:  2005 Mar-Apr       Impact factor: 0.788

3.  Donald F. Steiner MD, 1930-2014: discoverer of proinsulin.

Authors:  Louis H Philipson; Graeme Bell; Kenneth S Polonsky
Journal:  Proc Natl Acad Sci U S A       Date:  2015-01-05       Impact factor: 11.205

Review 4.  Precursors to regulatory peptides: their proteolytic processing.

Authors:  P C Andrews; K Brayton; J E Dixon
Journal:  Experientia       Date:  1987-07-15

5.  Isolation of a glucagon-containing peptide: primary structure of a possible fragment of proglucagon.

Authors:  H S Tager; D F Steiner
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

6.  Targeted Mass Spectrometry Approach Enabled Discovery of O-Glycosylated Insulin and Related Signaling Peptides in Mouse and Human Pancreatic Islets.

Authors:  Qing Yu; Alejandra Canales; Matthew S Glover; Rahul Das; Xudong Shi; Yang Liu; Mark P Keller; Alan D Attie; Lingjun Li
Journal:  Anal Chem       Date:  2017-08-07       Impact factor: 6.986

7.  Biomimetic synthesis of lispro insulin via a chemically synthesized "mini-proinsulin" prepared by oxime-forming ligation.

Authors:  Youhei Sohma; Stephen B H Kent
Journal:  J Am Chem Soc       Date:  2009-11-11       Impact factor: 15.419

8.  Endosomal proteolysis of internalised [ArgA0]-human insulin at neutral pH generates the mature insulin peptide in rat liver in vivo.

Authors:  M Kouach; B Desbuquois; F Authier
Journal:  Diabetologia       Date:  2009-10-16       Impact factor: 10.122

9.  Secretion and processing of insulin precursors in yeast.

Authors:  L Thim; M T Hansen; K Norris; I Hoegh; E Boel; J Forstrom; G Ammerer; N P Fiil
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

10.  Characterization of proinsulin-insulin intermediates in human plasma.

Authors:  C de Haën; S A Little; J M May; R H Williams
Journal:  J Clin Invest       Date:  1978-10       Impact factor: 14.808

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