Literature DB >> 4929535

Cross-linked transfer RNA functions in all steps of the translation process.

L J Chaffin, D R Omilianowski, R M Bock.   

Abstract

A specific photochemical reaction between 4-thiouridine and cytosine cross-links two arms of transfer RNA. This cross-link, introduced into phenylalanine transfer RNA and arginine transfer RNA, limits the conformational freedom of the molecule. Both modified transfer RNA's are capable of functioning in all steps of protein synthesis with this restraint on allowable conformations.

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Year:  1971        PMID： 4929535     DOI： 10.1126/science.172.3985.854

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  3 in total

1.  The general structure of transfer RNA molecules.

Authors:  S H Kim; J L Sussman; F L Suddath; G J Quigley; A McPherson; A H Wang; N C Seeman; A RICH
Journal:  Proc Natl Acad Sci U S A       Date:  1974-12       Impact factor: 11.205

2.  Mechanism of growth delay induced in Escherichia coli by near ultraviolet radiation.

Authors:  T V Ramabhadran; J Jagger
Journal:  Proc Natl Acad Sci U S A       Date:  1976-01       Impact factor: 11.205

3.  RNA under attack: cellular handling of RNA damage.

Authors:  Elisabeth J Wurtmann; Sandra L Wolin
Journal:  Crit Rev Biochem Mol Biol       Date:  2009 Jan-Feb       Impact factor: 8.250
  3 in total

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