Literature DB >> 4920654

Enzyme specificity as a factor in regulation of fatty acid chain length in Escherichia coli.

M D Greenspan, C H Birge, G Powell, W S Hancock, P R Vagelos.   

Abstract

Various acyl-acyl carrier protein intermediates in saturated and unsaturated fatty acid biosynthesis were tested as substrates for beta-ketoacyl-acyl carrier protein synthetase. With both classes of substrates the condensing enzyme in fatty biosynthesis demonstrates specificities which indicate that it might be an important factor in determining fatty acid chain length in Escherichia coli.

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Year:  1970        PMID: 4920654     DOI: 10.1126/science.170.3963.1203

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  4 in total

Review 1.  Physical properties of membrane lipids: biological relevance and regulation.

Authors:  J E Cronan; E P Gelmann
Journal:  Bacteriol Rev       Date:  1975-09

2.  Enzymology, genetics, and regulation of membrane phospholipid synthesis in Escherichia coli.

Authors:  C R Raetz
Journal:  Microbiol Rev       Date:  1978-09

3.  Fatty acid metabolism in sn-glycerol-3-phosphate acyltransferase (plsB) mutants.

Authors:  C L Cooper; S Jackowski; C O Rock
Journal:  J Bacteriol       Date:  1987-02       Impact factor: 3.490

4.  Chemical synthesis of acyl thioesters of acyl carrier protein with native structure.

Authors:  J E Cronan; A L Klages
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

  4 in total

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