| Literature DB >> 49185 |
M W Yocum, J Grossman, C Waterhouse, G N Abraham, A G May, J J Condemi.
Abstract
A pair of monozygotic twins discordant for systemic lupus erythematosus(SLE) were studied and no differences noted in their immune respose to tetanus toxoid, keyhole lympet hemocyanin, DNCB, delayed sensitivity, or antibody titers to viruses. Both were noted to have biologically false positive serology at an early age, but only one twon developed SLE. The clinically unaffected twin underwent castration at an early age, suggesting that ovarian hormones may play an important role in the development of SLE.Entities:
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Year: 1975 PMID： 49185 DOI： 10.1002/art.1780180301
Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591