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Literature DB >> 3830519

Abnormalities of sex hormones in men with systemic lupus erythematosus.

M Carrabba, C Giovine, M Chevallard, M Angelini, B Ambrosi, P Travaglini.

Abstract

Sex hormone concentrations were studied in 10 men with systemic lupus erythematosus (SLE) before and after HCG stimulation and compared with those of 10 healthy volunteers. The SLE men had significantly lower testosterone/estradiol ratios (before HCG test) and significantly lower mean increases in testosterone after HCG stimulation than the normals. Our findings confirm that there are sexual hormone abnormalities in SLE and suggest that these abnormal patterns may be important in the modulation of immune responses in SLE.

Entities: Chemical Disease Species

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Year: 1985 PMID： 3830519 DOI： 10.1007/bf02031894

Source DB: PubMed Journal: Clin Rheumatol ISSN： 0770-3198 Impact factor: 2.980

28 in total

1. A quantitative difference in the immune response between male and female mice.

Authors: G Terres; S L Morrison; G S Habicht
Journal: Proc Soc Exp Biol Med Date: 1968-03

2. Systemic lupus erythematosus associated with klinefelter's syndrome.

Authors: R Stern; J Fishman; H Brusman; H G Kunkel
Journal: Arthritis Rheum Date: 1977 Jan-Feb

3. Low plasma androgens in women with active or quiescent systemic lupus erythematosus.

Authors: P Jungers; K Nahoul; C Pelissier; M Dougados; F Tron; J F Bach
Journal: Arthritis Rheum Date: 1982-04

4. Estrogen metabolism in systemic lupus erythematosus: patients and family members.

Authors: R G Lahita; L Bradlow; J Fishman; H G Kunkel
Journal: Arthritis Rheum Date: 1982-07

5. Effect of estradiol on immune competence: in vivo and in vitro studies.

Authors: J F Kenny; P C Pangburn; G Trail
Journal: Infect Immun Date: 1976-02 Impact factor: 3.441

6. Monozygotic twins discordant for systemic lupus erythematosus.

Authors: M W Yocum; J Grossman; C Waterhouse; G N Abraham; A G May; J J Condemi
Journal: Arthritis Rheum Date: 1975 May-Jun

7. Hormonal manipulation of the immune response in systemic lupus erythematosus: a drug trial of an anabolic steroid, 19-nortestosterone.

Authors: R A Hazelton; A B McCruden; R D Sturrock; W H Stimson
Journal: Ann Rheum Dis Date: 1983-04 Impact factor: 19.103

8. Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice.

Authors: A D Steinberg; J B Roths; E D Murphy; R T Steinberg; E S Raveche
Journal: J Immunol Date: 1980-08 Impact factor: 5.422

9. Systemic lupus erythematosus: two patients treated with danazol.

Authors: K D Morley; A Parke; G R Hughes
Journal: Br Med J (Clin Res Ed) Date: 1982-05-15

10. Androgen sensitivity and autoimmune disease. I. Influence of sex and testosterone on the humoral immune response of autoimmune and non-autoimmune mouse strains to sheep erythrocytes.

Authors: J I Morton; D A Weyant; B V Siegel; B Golding
Journal: Immunology Date: 1981-12 Impact factor: 7.397

5 in total

Abnormalities of sex hormones in men with systemic lupus erythematosus.

1. A quantitative difference in the immune response between male and female mice.

2. Systemic lupus erythematosus associated with klinefelter's syndrome.

3. Low plasma androgens in women with active or quiescent systemic lupus erythematosus.

4. Estrogen metabolism in systemic lupus erythematosus: patients and family members.

5. Effect of estradiol on immune competence: in vivo and in vitro studies.

6. Monozygotic twins discordant for systemic lupus erythematosus.

7. Hormonal manipulation of the immune response in systemic lupus erythematosus: a drug trial of an anabolic steroid, 19-nortestosterone.

8. Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice.

9. Systemic lupus erythematosus: two patients treated with danazol.

10. Androgen sensitivity and autoimmune disease. I. Influence of sex and testosterone on the humoral immune response of autoimmune and non-autoimmune mouse strains to sheep erythrocytes.

1. Sex differences in statural growth impairment in Crohn's disease: role of IGF-1.

2. Sex hormone concentrations in male patients with ankylosing spondylitis: preliminary report.

Review 3. Autoimmune diseases and reproductive aging.

4. Klinefelter's syndrome and lupus erythematosus: report of a case.

Review 5. Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics.