| Literature DB >> 4911774 |
D Hughes, P C Elwood, N K Shinton, R J Wrighton.
Abstract
A clinical trial of the effect of vitamin B(12) therapy was conducted in 39 elderly subjects who had been found, in a community screening survey, to have low levels of serum B(12) without a macrocytic anaemia or neuropathy. The study produced no evidence which suggests that in such subjects B(12) is superior to placebo in effecting an improvement in psychiatric state or general well-being. There was a clear tendency for all the subjects to show an improvement during the trial, but this probably represents the therapeutic effect of involvement in a research exercise of this kind.Entities:
Mesh：
Substances：
Year: 1970 PMID： 4911774 PMCID： PMC1700490 DOI： 10.1136/bmj.2.5707.458
Source DB: PubMed Journal: Br Med J ISSN： 0007-1447