Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Pepsinogens: genetic polymorphism in man.

Literature DB >> 4906786

Pepsinogens: genetic polymorphism in man.

Abstract

Population frequencies of the two patterns of pepsinogen excretion (with and without pepsinogen 5) and family studies indicate that pepsinogen 5 is controlled by a pair of genes, Pg(a) and Pg(b), at a single autosomal locus and that Pg(a) is dominant.

Entities: Gene Species

Mesh：

Substances：

Year: 1970 PMID： 4906786 DOI： 10.1126/science.168.3927.144

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

Keyword Cloud
Cited

27 in total

1. Probable genetic linkage between a locus for human urinary pepsinogen and the HL-A loci.

Authors: L R Weitkamp; P L Townes; A G May
Journal: Am J Hum Genet Date: 1975-07 Impact factor: 11.025

2. Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

Authors: A Zwiers; C Toonstra; G Pals; A J Donker; S G Meuwissen; R W ten Kate
Journal: J Clin Pathol Date: 1990-10 Impact factor: 3.411

3. Newly characterized genetic polymorphism of uropepsinogen group A (PGA) using both isoelectric focusing and immunoblotting.

Authors: K Kishi; T Yasuda
Journal: Hum Genet Date: 1987-03 Impact factor: 4.132

4. Molecular cloning of a pair of human pepsinogen A genes which differ by a Glu----Lys mutation in the activation peptide.

Authors: M P Evers; B Zelle; D S Peeper; W H Mager; R J Planta; A W Eriksson; R R Frants
Journal: Hum Genet Date: 1987-10 Impact factor: 4.132

5. Relationships between the human pepsinogen DNA and protein polymorphisms.

Authors: R T Taggart; I M Samloff; L J Raffel; A Graham; C Cass; G M Petersen; J I Rotter; M H Skolnick; C E Schwartz; G I Bell
Journal: Am J Hum Genet Date: 1986-06 Impact factor: 11.025

6. Discrepancies between gastric mucosal and urinary pepsinogen A patterns and in vitro synthesis and secretion of human pepsinogen.

Authors: G Pals; B D Westerveld; J Defize; J C Pronk; H Brand; M Flipse; C Verwey; S G Meuwissen; A W Eriksson
Journal: Dig Dis Sci Date: 1988-02 Impact factor: 3.199

Pepsinogens: genetic polymorphism in man.

1. Probable genetic linkage between a locus for human urinary pepsinogen and the HL-A loci.

2. Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

3. Newly characterized genetic polymorphism of uropepsinogen group A (PGA) using both isoelectric focusing and immunoblotting.

4. Molecular cloning of a pair of human pepsinogen A genes which differ by a Glu----Lys mutation in the activation peptide.

5. Relationships between the human pepsinogen DNA and protein polymorphisms.

6. Discrepancies between gastric mucosal and urinary pepsinogen A patterns and in vitro synthesis and secretion of human pepsinogen.

7. The preparation and purification of individual human pepsins by using diethylaminoethyl-cellulose.

8. Simultaneous electrophoresis of pepsinogens and pepsins.

9. Pepsinogen synthesis and secretion in isolated gastric glands.

10. Genetic variation of pepsinogen 1 in the rat.