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Literature DB >> 4897023

A factor that stimulates RNA synthesis by purified RNA polymerase.

Abstract

A protein factor, partially purified from E. coli, can stimulate some 30- to 50-fold the transcription of DNA by purified RNA polymerase. Evidence is presented suggesting that this stimulatory factor (designated M factor) exerts its effect before the RNA synthesis is initiated. The M factor is prepared from a crude ribosome fraction, but it does not require the presence of ribosomes for full activity.

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Year: 1969 PMID： 4897023 PMCID： PMC534018 DOI： 10.1073/pnas.63.1.168

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

13 in total

1. The transformation of Escherichia coli with deoxyribonucleic acid isolated from bacteriophage lambda-dg.

Authors: A D KAISER; D S HOGNESS
Journal: J Mol Biol Date: 1960-12 Impact factor: 5.469

2. ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID.

Authors: S B Weiss
Journal: Proc Natl Acad Sci U S A Date: 1960-08 Impact factor: 11.205

3. Factor stimulating transcription by RNA polymerase.

Authors: R R Burgess; A A Travers; J J Dunn; E K Bautz
Journal: Nature Date: 1969-01-04 Impact factor: 49.962

4. Role of protein factor in the functional binding of ribosomes to natural messenger RNA.

Authors: M Revel; M Herzberg; A Becarevic; F Gros
Journal: J Mol Biol Date: 1968-04-14 Impact factor: 5.469

5. Influence of salts on RNA synthesis by DNA-dependent RNA-polymerase from Escherichia coli.

Authors: R L Millette; W Zillig; G Walter
Journal: Eur J Biochem Date: 1967-12

6. Effects of cations on DNA-dependent RNA polymerase.

Authors: A G So; E W Davie; R Epstein; A Tissières
Journal: Proc Natl Acad Sci U S A Date: 1967-10 Impact factor: 11.205

7. Ribosomes from a streptomycin-dependent strain of Escherichia coli.

Authors: T E Lekover; C G Kurland
Journal: J Mol Biol Date: 1967-05-14 Impact factor: 5.469

8. Isolation and characterization of ribonuclease I mutants of Escherichia coli.

Authors: R F Gesteland
Journal: J Mol Biol Date: 1966-03 Impact factor: 5.469

9. Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences.

Authors: A R Morgan; R D Wells
Journal: J Mol Biol Date: 1968-10-14 Impact factor: 5.469

6. In vitro synthesis of enzymes of the tryptophan operon of Escherichia coli. Evidence for positive control of transcription.

Authors: P H Pouwels; J van Rotterdam
Journal: Mol Gen Genet Date: 1975

7. Substrate-binding ability of Escherichia coli ribonucleic acid polymerase in relation to its protein composition.

Authors: A Rognes; K A Abraham
Journal: Biochem J Date: 1976-01-01 Impact factor: 3.857

8. Stimulation of RNA synthesis by two protein factors in extracts of Escherichia coli.

Authors: Y Murooka; R A Lazzarini
Journal: Proc Natl Acad Sci U S A Date: 1972-08 Impact factor: 11.205

8 in total

A factor that stimulates RNA synthesis by purified RNA polymerase.

1. The transformation of Escherichia coli with deoxyribonucleic acid isolated from bacteriophage lambda-dg.

2. ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID.

3. Factor stimulating transcription by RNA polymerase.

4. Role of protein factor in the functional binding of ribosomes to natural messenger RNA.

5. Influence of salts on RNA synthesis by DNA-dependent RNA-polymerase from Escherichia coli.

6. Effects of cations on DNA-dependent RNA polymerase.

7. Ribosomes from a streptomycin-dependent strain of Escherichia coli.

8. Isolation and characterization of ribonuclease I mutants of Escherichia coli.

9. Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences.

10. A new method for the purification of RNA-polymerase.

1. Escherichia coli mutant strain with altered expression of the tryptophan operon: ribonucleic acid synthesis in vitro.

2. Purification and properties of D protein: a transcription factor of Escherichia coli.

3. Stimulation of DNA-dependent RNA synthesis by a protein associated with ribosomes.

4. DNA-directed synthesis in vitro of beta-galactosidase: requirement for a ribosome release factor.

5. Reinitiation of RNA synthesis on transcription of chromatin DNA by Escherichia coli RNA polymerase.

6. In vitro synthesis of enzymes of the tryptophan operon of Escherichia coli. Evidence for positive control of transcription.

7. Substrate-binding ability of Escherichia coli ribonucleic acid polymerase in relation to its protein composition.

8. Stimulation of RNA synthesis by two protein factors in extracts of Escherichia coli.