Literature DB >> 4896309

Hormonal stimulation of lactose synthetase in mammary carcinoma.

W L McGuire.   

Abstract

A transplantable rat mammary carcinoma (R3230AC) synthesizes significant quantities of the mammary gland enzyme lactose synthetase in the immature virgin female rat. In this hormonal environment, mammary glands do not synthesize the enzyme. Prolactin further stimulates the enzyme activity in the tumors to levels found only in mammary glands of rats in late pregnancy or during lactation.

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Year:  1969        PMID： 4896309     DOI： 10.1126/science.165.3897.1013

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  4 in total

1.  Reactivity of a monoclonal antibody recognizing an estrogen receptor regulated glycoprotein in relation to lectin histochemistry in breast cancer.

Authors:  M Helle; K Krohn
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

2.  Alkaline ribonuclease and ribonuclease inhibitor in mammary gland during the lactation cycle and in the R3230AC mammary tumour.

Authors:  D K Liu; G H Williams; P J Fritz
Journal:  Biochem J       Date:  1975-04       Impact factor: 3.857

3.  Ca2+-stimulated ribonuclease. A new marker enzyme of differentiated rat mammary tissues.

Authors:  D K Liu; D Kulick; G H Williams
Journal:  Biochem J       Date:  1979-01-15       Impact factor: 3.857

4.  Demonstration of a glucocorticoid hormone-receptor complex in the cytoplasm of a hormone-responsive tumour.

Authors:  D G Gardner; J L Wittliff
Journal:  Br J Cancer       Date:  1973-06       Impact factor: 7.640
  4 in total

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