Literature DB >> 4891260

Chloramphenicol and the stimulation of ribonucleic acid synthesis in Escherichia coli.

S Kaplan.   

Abstract

Data have been obtained which imply that chloramphenicol stimulation of ribonucleic acid (RNA) synthesis is a result of the accumulation of aminoacyl transfer RNA (tRNA) molecules. The data also support the hypothesis that chloramphenicol exerts an additional effect upon the stimulation of RNA synthesis. This effect may be at the level of the ribosome or the aminoacyl tRNA, or of both. It is this effect combined with the presence of aminoacyl tRNA that results in stimulation by chloramphenicol of RNA synthesis.

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Year:  1969        PMID： 4891260      PMCID： PMC284858          DOI： 10.1128/jb.98.2.587-592.1969

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  9 in total

1.  Control of RNA synthesis in Escherichia coli. I. Amino acid dependence of the synthesis of the substrates of RNA polymerase.

Authors:  M Cashel; J Gallant
Journal:  J Mol Biol       Date:  1968-07-14       Impact factor: 5.469

Review 2.  Physiology and genetics of the "ribonucleic acid control" locus in escherichia coli.

Authors:  G Edlin; P Broda
Journal:  Bacteriol Rev       Date:  1968-09

3.  Selection of temperature-sensitive activating enzyme mutants in Escherichia coli.

Authors:  S Kaplan; D Anderson
Journal:  J Bacteriol       Date:  1968-03       Impact factor: 3.490

4.  Correlation between the rate of ribonucleic acid synthesis and the level of valyl transfer ribonucleic acid in mutants of Escherichia coli.

Authors:  S Kaplan
Journal:  J Bacteriol       Date:  1969-05       Impact factor: 3.490

Review 5.  Roles of amino acid activating enzymes in cellular physiology.

Authors:  F C Neidhardt
Journal:  Bacteriol Rev       Date:  1966-12

6.  The inhibition by chloramphenicol of nascent protein formation in E. coli.

Authors:  M J Weber; J A DeMoss
Journal:  Proc Natl Acad Sci U S A       Date:  1966-05       Impact factor: 11.205

7.  Control of ribonucleic acid synthesis in Escherichia coli cells with altered transfer ribonucleic acid concentration.

Authors:  D H Ezekiel; B Valulis
Journal:  Biochim Biophys Acta       Date:  1966-10-24

8.  Polysome transitions and the regulation of ribonucleic acid synthesis in Escherichia coli.

Authors:  D W Morris; J A DeMoss
Journal:  Proc Natl Acad Sci U S A       Date:  1966-07       Impact factor: 11.205

9.  Role of aminoacyl-transfer ribonucleic acid in the regulation of ribonucleic acid synthesis in Escherichia coli.

Authors:  D W Morris; J A DeMoss
Journal:  J Bacteriol       Date:  1965-12       Impact factor: 3.490
  9 in total
  2 in total

1.  Correlation between the rate of ribonucleic acid synthesis and the level of valyl transfer ribonucleic acid in mutants of Escherichia coli.

Authors:  S Kaplan
Journal:  J Bacteriol       Date:  1969-05       Impact factor: 3.490

2.  Effect of serine hydroxamate on phospholipid synthesis in Escherichia coli.

Authors:  L I Pizer; J P Merlie
Journal:  J Bacteriol       Date:  1973-06       Impact factor: 3.490
  2 in total

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