| Literature DB >> 488710 |
Abstract
The infinite-sites model with no recombination is extended to include mutations that affect electrophoretic mobility. The model allows the effect of a single-site mutation to have a continuous effect on mobility. Formulae are obtained for the variance of electrophoretic mobility of alleles after an arbitrary lenght of time. A special case of the general model is the case of stepwise production of neutral alleles with an arbitrary number of steps.Mesh:
Year: 1979 PMID: 488710 PMCID: PMC1213983
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562