Literature DB >> 488710

A model allowing continuous variation in electrophoretic mobility of neutral alleles.

G Cobbs.   

Abstract

The infinite-sites model with no recombination is extended to include mutations that affect electrophoretic mobility. The model allows the effect of a single-site mutation to have a continuous effect on mobility. Formulae are obtained for the variance of electrophoretic mobility of alleles after an arbitrary lenght of time. A special case of the general model is the case of stepwise production of neutral alleles with an arbitrary number of steps.

Mesh:

Year:  1979        PMID: 488710      PMCID: PMC1213983     

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  4 in total

1.  The charge-state model of protein polymorphism in natural populations.

Authors:  D R Marshall; A H Brown
Journal:  J Mol Evol       Date:  1975-11-04       Impact factor: 2.395

2.  Allelic heterogeneity within allozymes separated by electrophoresis in Drosophila pseudoobscura.

Authors:  R E McDowell; S Prakash
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

3.  Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles.

Authors:  M Kimura; T Ohta
Journal:  Proc Natl Acad Sci U S A       Date:  1975-07       Impact factor: 11.205

4.  Wandering distributions and the electrophoretic profile.

Authors:  P A Moran
Journal:  Theor Popul Biol       Date:  1975-12       Impact factor: 1.570

  4 in total

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